Michelangelo Lassandro
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miclass.bsky.social
Michelangelo Lassandro
@miclass.bsky.social
PhD student in Structural Biology at Human Technopole, Milan, Italy. Passionate about RNA related world.
Reposted by Michelangelo Lassandro
🥳Today at HT, we took the time to celebrate one another, recognising colleagues who have stood out for their contributions or positive attitude.

👏Congratulations to the winners: Roberto Zigiotto (Above & Beyond Award) and @giovannimaltinti.bsky.social (Good Vibes Award)!
January 22, 2025 at 3:12 PM
Reposted by Michelangelo Lassandro
Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...

A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications
The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...
www.nature.com
January 3, 2025 at 10:37 AM
Reposted by Michelangelo Lassandro
JOB ALERT!!! The National Facility for Structural Biology at @humantechnopole.bsky.social is HIRING!! BlueSky-less Andrea Graziadei is looking for a technician to join his Unit and push #structuralproteomics to new, uncharted territories!! 1/3
December 5, 2024 at 9:23 AM
Reposted by Michelangelo Lassandro
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
www.nature.com
November 18, 2024 at 11:06 AM