Simon Michaeli
@michaelilab.bsky.social
Plant and cell biologist. Interested in 🔬 organelles, membrane trafficking, autophagy, 🌿🍂 senescence, 🍑 ripening, learning, teaching and much more 🪐
https://www.michaelilab.com/
https://www.michaelilab.com/
A short #research highlight on the intriguing, complex and potentially dual role of #autophagy in fruit ripening:
#plantscience
rdcu.be/eOY3h
#plantscience
rdcu.be/eOY3h
November 10, 2025 at 1:06 PM
A short #research highlight on the intriguing, complex and potentially dual role of #autophagy in fruit ripening:
#plantscience
rdcu.be/eOY3h
#plantscience
rdcu.be/eOY3h
A bit more of my Chengdu experience
October 23, 2025 at 7:04 AM
A bit more of my Chengdu experience
Probably the best urinal point in the world...
Tanglang mountain in Shenzhen
Tanglang mountain in Shenzhen
October 22, 2025 at 7:27 AM
Probably the best urinal point in the world...
Tanglang mountain in Shenzhen
Tanglang mountain in Shenzhen
How you say you're in a conference in Chengdu without saying you're in a conference in Chengdu...
October 14, 2025 at 6:56 AM
How you say you're in a conference in Chengdu without saying you're in a conference in Chengdu...
Hearing the good news from my country while in Chengdu. Much nicer to start the symposium on the plant hormone #ethylene tomorrow under these circumstances 🎉
October 13, 2025 at 12:00 PM
Hearing the good news from my country while in Chengdu. Much nicer to start the symposium on the plant hormone #ethylene tomorrow under these circumstances 🎉
Yes, everything as usual now...
June 28, 2025 at 10:50 AM
Yes, everything as usual now...
June 11, 2025 at 3:40 PM
June 10, 2025 at 11:02 AM
Even now, in these troubling times, Israel is still the only country in the Middle-East that marks and celebrates #PRIDEmonth. Wishing Queer Jews, Muslims, Christians, Druze, Atheists and all others in Israel, the M-E and beyond the best, and better days ahead. Remember, we're not our government!
June 8, 2025 at 8:31 AM
Even now, in these troubling times, Israel is still the only country in the Middle-East that marks and celebrates #PRIDEmonth. Wishing Queer Jews, Muslims, Christians, Druze, Atheists and all others in Israel, the M-E and beyond the best, and better days ahead. Remember, we're not our government!
Beautiful Rhodes 🇬🇷
May 17, 2025 at 7:35 AM
Beautiful Rhodes 🇬🇷
3. ACC and ethylene induce autophagy activity
May 9, 2025 at 12:00 PM
3. ACC and ethylene induce autophagy activity
2. They are more sensitive to ACC (ethylene's precursor)
May 9, 2025 at 12:00 PM
2. They are more sensitive to ACC (ethylene's precursor)
We were still skeptical about the ethylene direction until we realized the autophagy impact on ethylene may be broader, beyond ripening.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
May 9, 2025 at 12:00 PM
We were still skeptical about the ethylene direction until we realized the autophagy impact on ethylene may be broader, beyond ripening.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
One of the coolest things we saw was that fruits deficient in different ripening genes (upstream or downstream of ethylene) show different autophagy activity.
May 9, 2025 at 12:00 PM
One of the coolest things we saw was that fruits deficient in different ripening genes (upstream or downstream of ethylene) show different autophagy activity.
But what about ethylene? Its production from ATG4-silenced fruits started climbing a few days before wild-type fruits. Then, when we applied 1-MCP, an ethylene antagonist, we saw the mutants behave as the WT.
May 9, 2025 at 12:00 PM
But what about ethylene? Its production from ATG4-silenced fruits started climbing a few days before wild-type fruits. Then, when we applied 1-MCP, an ethylene antagonist, we saw the mutants behave as the WT.
This, together with another approach (Virus-Induced gene silencing of other ATG genes), revealed that autophagy restricts ripening. This was surprising to us, as it was in contrast to other previous reports in climacteric and nonclimacteric fruits.
May 9, 2025 at 12:00 PM
This, together with another approach (Virus-Induced gene silencing of other ATG genes), revealed that autophagy restricts ripening. This was surprising to us, as it was in contrast to other previous reports in climacteric and nonclimacteric fruits.
1st, we analyzed autophagy's activity and saw that it's increasing along ripening from essentially 0 when fruits are mature green up to impressive activity at mid the process. The collaboration from @suaybuestuen.bsky.social and former lab members
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
May 9, 2025 at 12:00 PM
1st, we analyzed autophagy's activity and saw that it's increasing along ripening from essentially 0 when fruits are mature green up to impressive activity at mid the process. The collaboration from @suaybuestuen.bsky.social and former lab members
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
Studying fruit ripening is important for many (agronomic, economic, and environmental) reasons. In addition, we thought that climacteric fruit ripening, heavily relying on the hormone ethylene, may reveal the nature of autophagy-ethylene interaction (long suggested).
May 9, 2025 at 12:00 PM
Studying fruit ripening is important for many (agronomic, economic, and environmental) reasons. In addition, we thought that climacteric fruit ripening, heavily relying on the hormone ethylene, may reveal the nature of autophagy-ethylene interaction (long suggested).
📢 It's online (and open access) @newphyt.bsky.social
🍅
nph.onlinelibrary.wiley.com/doi/full/10....
"Autophagy restricts tomato fruit ripening via a general role in ethylene repression"
& why timing is everything...
Let's dig into it 👇
#plantscience
#autophagy
@volcaniinstitute.bsky.social
🍅
nph.onlinelibrary.wiley.com/doi/full/10....
"Autophagy restricts tomato fruit ripening via a general role in ethylene repression"
& why timing is everything...
Let's dig into it 👇
#plantscience
#autophagy
@volcaniinstitute.bsky.social
May 9, 2025 at 12:00 PM
📢 It's online (and open access) @newphyt.bsky.social
🍅
nph.onlinelibrary.wiley.com/doi/full/10....
"Autophagy restricts tomato fruit ripening via a general role in ethylene repression"
& why timing is everything...
Let's dig into it 👇
#plantscience
#autophagy
@volcaniinstitute.bsky.social
🍅
nph.onlinelibrary.wiley.com/doi/full/10....
"Autophagy restricts tomato fruit ripening via a general role in ethylene repression"
& why timing is everything...
Let's dig into it 👇
#plantscience
#autophagy
@volcaniinstitute.bsky.social
This is Horvat Aqav, the remains of a manor, which was inhabited by Jews until the second half of the 1st century CE. The site was resettled by the Byzantines (4th to 7th CE) until the Muslim conquest. Whoever the owners were, they sure knew how to choose a spot. What a view to the Mediterranean
May 2, 2025 at 12:44 PM
This is Horvat Aqav, the remains of a manor, which was inhabited by Jews until the second half of the 1st century CE. The site was resettled by the Byzantines (4th to 7th CE) until the Muslim conquest. Whoever the owners were, they sure knew how to choose a spot. What a view to the Mediterranean
The Red Canyon near Eilat
April 15, 2025 at 6:10 PM
The Red Canyon near Eilat
Surrounded by some amazing people (and a dog!) at the Volcani Institute 🥂🍾🍅
April 4, 2025 at 8:17 AM
Surrounded by some amazing people (and a dog!) at the Volcani Institute 🥂🍾🍅