Mariana Harris
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mharris.bsky.social
Mariana Harris
@mharris.bsky.social
Biomath PhD @UCLA interested in population genetics
Reposted by Mariana Harris
A large-scale genomic study in Science of over 1500 individuals from 139 underrepresented Indigenous groups across northern Eurasia and the Americas sheds new light on the ancient migrations that shaped the genetic landscape of North and South America.

Learn more: scim.ag/4mi1yUf
From North Asia to South America: Tracing the longest human migration through genomic sequencing
Genome sequencing of 1537 individuals from 139 ethnic groups reveals the genetic characteristics of understudied populations in North Asia and South America. Our analysis demonstrates that West Siberi...
scim.ag
May 16, 2025 at 1:12 PM
Reposted by Mariana Harris
Thrilled to share that our study on the genetic architecture and evolutionary constraints shaping human pelvic form is now out in Science(@science.org)! This work was brilliantly led by my lab mate @xliaoyi.bsky.social

Check it out here:
www.science.org/doi/10.1126/...
The genetic architecture of and evolutionary constraints on the human pelvic form
Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical ...
www.science.org
April 11, 2025 at 2:50 PM
Reposted by Mariana Harris
Delighted to share that our paper on discovering selective sweeps with haplotype statistics in aDNA is now out in Nat. Comm! www.nature.com/articles/s41...

Wonderful collaboration with Vagheesh Narasimhan, Devansh Pandey, and @mharris.bsky.social
Leveraging ancient DNA to uncover signals of natural selection in Europe lost due to admixture or drift - Nature Communications
Large-scale ancient DNA (aDNA) studies offer the chance to examine genomic changes over time, providing direct insights into human evolution. Here the authors use aDNA from 708 European samples to ide...
www.nature.com
November 13, 2024 at 4:49 PM
Reposted by Mariana Harris
I'm so excited to share this new paper (with my great advisor @nanditagarud.bsky.social), on selective sweeps in gut bacteria. In this long thread, I’m going to go over our results, but I also want to highlight some of the incredible work that set the stage for us

www.biorxiv.org/content/10.1...
Pervasive selective sweeps across human gut microbiomes
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
January 3, 2024 at 11:12 PM
Reposted by Mariana Harris
We are delighted to share our work on “Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history”! www.biorxiv.org/content/10.1... Please check out the full tweet thread and GIF here: twitter.com/nanditagarud...
November 14, 2023 at 9:29 PM