Michael G. Lerner
@mglerner.bsky.social
Comp. biophysicist at Earlham: Biomembranes, comp oncology. Reducing distracted hyperbusyness. Decolonizing my sylabus. mglerner@pm.me @mglerner@mastodon.cloud @mglerner at bird site
ORCID: 0000-0003-1222-3212
ORCID: 0000-0003-1222-3212
I know this is not the question. But do we know the mechanism yet?
We don't just have evidence that ibuprofen works, we have things like a cochrane review finding two high-quality RCTs showing ibuprofen works better than acetaminophen for dental pain after lower wisdom tooth removal. www.cochranelibrary.com/cdsr/doi/10....
November 14, 2025 at 2:38 AM
I know this is not the question. But do we know the mechanism yet?
It's angular momentum day in my #Physics class, so of course we start with fidget spinners on their desks and Emmy Noether on the screen as they walk into the room :)
November 5, 2025 at 2:38 PM
It's angular momentum day in my #Physics class, so of course we start with fidget spinners on their desks and Emmy Noether on the screen as they walk into the room :)
why would you do this
October 14, 2025 at 8:48 PM
why would you do this
I asked what turned out to be a really hard question in my intro class. Build this circuit on a breadboard (easy). Measure the equivalent resistance of the two parallel resistors (easy). Measure I1, the current through R1 (whoa!).
#ITeachPhysics a lot, and I was surprised by just how tough this was.
#ITeachPhysics a lot, and I was surprised by just how tough this was.
October 8, 2025 at 1:21 PM
I asked what turned out to be a really hard question in my intro class. Build this circuit on a breadboard (easy). Measure the equivalent resistance of the two parallel resistors (easy). Measure I1, the current through R1 (whoa!).
#ITeachPhysics a lot, and I was surprised by just how tough this was.
#ITeachPhysics a lot, and I was surprised by just how tough this was.
Reposted by Michael G. Lerner
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
September 26, 2025 at 3:35 PM
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
This may well be the most fascinating job post I've ever seen! A whole (short) thread worth reading, and getting excited about. Whether or not you're a relevant candidate.
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
September 26, 2025 at 4:02 PM
This may well be the most fascinating job post I've ever seen! A whole (short) thread worth reading, and getting excited about. Whether or not you're a relevant candidate.
Reposted by Michael G. Lerner
Major cool membrane conference coming up next week! The Biomembrane Days 2025, organized by an amazing team from the MPI for Colloids and Interface Science @mpici.bsky.social: Rumy Dimova (@dimovalab.bsky.social), Helge Ewers, and Thomas Weikl. I'm so very much looking forward to attending! 🤩 🧪
Biomembrane Days 2025
Membranes form the intricately shaped compartments of life. The Biomembrane Days are a triannual workshop that highlights recent advances in understanding the morphology and molecular organization of ...
events.mpikg.mpg.de
September 23, 2025 at 2:15 PM
Major cool membrane conference coming up next week! The Biomembrane Days 2025, organized by an amazing team from the MPI for Colloids and Interface Science @mpici.bsky.social: Rumy Dimova (@dimovalab.bsky.social), Helge Ewers, and Thomas Weikl. I'm so very much looking forward to attending! 🤩 🧪
Yet again, someone’s off leash dog attacked mine on a walk. Of course it had to be something as muscular as a pitt bull. Everyone’s fine. But I’m getting too old to throw my boat in the middle of dog fights.
September 11, 2025 at 3:45 AM
Yet again, someone’s off leash dog attacked mine on a walk. Of course it had to be something as muscular as a pitt bull. Everyone’s fine. But I’m getting too old to throw my boat in the middle of dog fights.
I love this question for intro physics
![Projectiles 1 and 2 are launched over level ground with the same speed but at different angles. Which hits the ground first? Ignore air resistance. [Projectile 1 goes about twice as high as projectile 2, both in nice parabolic arcs.]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:2s32idzwnqpln3s44jz5dvy6/bafkreieiedlbihyluoehrnzw6owxr7rzhzhn6m45pdmklo2uurkkodwapa@jpeg)
September 8, 2025 at 12:49 PM
I love this question for intro physics
Slightly late to this, but I’m watching the Fast and Furious movies for the first time. I’m on #3. The series seems to think we’re watching for Paul Walker. Are they serious?!
August 24, 2025 at 2:28 AM
Slightly late to this, but I’m watching the Fast and Furious movies for the first time. I’m on #3. The series seems to think we’re watching for Paul Walker. Are they serious?!
Reposted by Michael G. Lerner
Tour de force on the kinetics and mechansms of lipid transport in cells through exquisite use of bifunctional probes by @nadlerlab.bsky.social and colleagues. Such an exciting time for the field. www.nature.com/articles/s41...
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 21, 2025 at 2:07 AM
Tour de force on the kinetics and mechansms of lipid transport in cells through exquisite use of bifunctional probes by @nadlerlab.bsky.social and colleagues. Such an exciting time for the field. www.nature.com/articles/s41...
Reposted by Michael G. Lerner
We are hiring into 3 (THREE!) tenure track lines this year at Wake Forest — if you’re looking please reach out, I love chatting about our department! We are a vibrant group that love & embrace the teacher-scholar model 👩🏫
August 20, 2025 at 11:46 AM
We are hiring into 3 (THREE!) tenure track lines this year at Wake Forest — if you’re looking please reach out, I love chatting about our department! We are a vibrant group that love & embrace the teacher-scholar model 👩🏫
Found an old box of tapes. Now listening to the Soup Dragons.
August 5, 2025 at 6:01 PM
Found an old box of tapes. Now listening to the Soup Dragons.
Reposted by Michael G. Lerner
Can’t wait to introduce bird-based storage into my backup system
July 28, 2025 at 2:06 PM
Can’t wait to introduce bird-based storage into my backup system
A friend has pointed out that “stare at it and be smart” is a very generally applicable method
Middle-aged folks: how did you learn to factor polynomials like ax^2 + bx + c? My kids have learned the diamond and box methods. I'm pretty sure I just learned "stare it and be smart."
July 17, 2025 at 9:37 PM
A friend has pointed out that “stare at it and be smart” is a very generally applicable method
Middle-aged folks: how did you learn to factor polynomials like ax^2 + bx + c? My kids have learned the diamond and box methods. I'm pretty sure I just learned "stare it and be smart."
July 17, 2025 at 8:14 PM
Middle-aged folks: how did you learn to factor polynomials like ax^2 + bx + c? My kids have learned the diamond and box methods. I'm pretty sure I just learned "stare it and be smart."
Reposted by Michael G. Lerner
Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Dwell time is especially sensitive to spacing between DNA targets. Nonspecific binding and facilitated (1D) diffusion also play a key role. Super proud of Mankun Sang’s work!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
July 11, 2025 at 4:23 PM
Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Dwell time is especially sensitive to spacing between DNA targets. Nonspecific binding and facilitated (1D) diffusion also play a key role. Super proud of Mankun Sang’s work!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Michael G. Lerner
🖥️🧬I have a tool/lib that I want to make that I think will be useful. But, all of my students are busy with projects. While I have a plan & cycles to help, it will take way longer if I do it all myself. It needs to be written in Rust & be fast. If you’re interested in learning more, please ping me!
June 25, 2025 at 2:55 PM
🖥️🧬I have a tool/lib that I want to make that I think will be useful. But, all of my students are busy with projects. While I have a plan & cycles to help, it will take way longer if I do it all myself. It needs to be written in Rust & be fast. If you’re interested in learning more, please ping me!
Amazing
The Banach-Barkski Pair-of-dogs
June 22, 2025 at 5:25 PM
Amazing
Reposted by Michael G. Lerner
The Banach-Barkski Pair-of-dogs
June 22, 2025 at 4:15 PM
The Banach-Barkski Pair-of-dogs
Reposted by Michael G. Lerner
This is a very big scientific milestone: stem cells appear to have permanently cured most diabetics in this small but historic trial based on the work of Harvard researcher Doug Melton, who has 2 kids with diabetes. www.nytimes.com/2025/06/20/h...
People With Severe Diabetes Are Cured in Small Trial of New Drug
www.nytimes.com
June 21, 2025 at 11:29 AM
This is a very big scientific milestone: stem cells appear to have permanently cured most diabetics in this small but historic trial based on the work of Harvard researcher Doug Melton, who has 2 kids with diabetes. www.nytimes.com/2025/06/20/h...