Melvin Noe Gonzalez
@melv-noe-gonzalez.bsky.social
Husband. Father. Postdoc @ Svejstrup lab in Copenhagen studying transcription and DNA damage | EMBO & MSCA fellow
Jarocho de corazón, biochemist by training 🇲🇽
Jarocho de corazón, biochemist by training 🇲🇽
Anouk's tour-de-force includes degrons, imaging, mass spec, flow cytometry, and LOTS of sequencing, which all lead to the conclusion that abundance of RNAPII is actively sensed by the cell, and these levels are regulated to ensure steady-state gene expression.
September 19, 2025 at 9:15 AM
Anouk's tour-de-force includes degrons, imaging, mass spec, flow cytometry, and LOTS of sequencing, which all lead to the conclusion that abundance of RNAPII is actively sensed by the cell, and these levels are regulated to ensure steady-state gene expression.
Congrats on the first paper from your lab! 🍾
December 12, 2024 at 9:02 PM
Congrats on the first paper from your lab! 🍾
Have had good luck with the SMASH system to use in parallel with drag
pmc.ncbi.nlm.nih.gov/articles/PMC...
Only issue of course is the half-life of your protein…
pmc.ncbi.nlm.nih.gov/articles/PMC...
Only issue of course is the half-life of your protein…
Tunable and reversible drug control of protein production via a self-excising degron
An effective method for direct chemical control over the production of specific proteins would be widely useful. We describe Small Molecule-Assisted Shutoff (SMASh), a technique in which proteins are ...
pmc.ncbi.nlm.nih.gov
November 21, 2024 at 4:52 PM
Have had good luck with the SMASH system to use in parallel with drag
pmc.ncbi.nlm.nih.gov/articles/PMC...
Only issue of course is the half-life of your protein…
pmc.ncbi.nlm.nih.gov/articles/PMC...
Only issue of course is the half-life of your protein…