3 million child deaths were linked to rising antimicrobial resistance. Africa & Asia are the most impacted regions. The growing threat of AMR is one of most consequential threats to global public health. Another reason to invest & not defund research.
www-bbc-com.cdn.ampproject.org/c/s/www.bbc....

A really cool study just published used metagenomic sequencing to uncover viral causes of unexplained fevers in Uganda. Of 230 patients who had tested negative for common infections, 19% had viral pathogens—ranging from respiratory and GI viruses to deadly viruses.
www.nature.com/articles/s41...

So much of the cutting that has been happening in US-government funded science threatens the future of scientific discovery in this country. @usha.bsky.social reports on yet another, the termination of a summer internship program at #NIH for college students. www.statnews.com/2025/03/05/t...

www.statnews.com/2025/03/01/p...

And then there's gonorrhea.

It has developed resistance to nearly all antibiotics used against it—we're down to one last recommended and effective class

-> 600K+ cases reported in the US each year
-> Medicaid helps those most at risk with testing & treatment, which is crucial to stop resistance

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

Much love and support to my colleagues at the CDC and NIH who are probably super unsure what’s going on, don’t know how it’s affecting their programs, but somehow have to keep doing their day to day because the work is important and people depend on them. ❤️ #IDsky

“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO

Just notified that the 2025 Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) meeting was cancelled as a result of this.

Valuable meeting on antimicrobial resistance & such a disappointment this is cancelled.

#IDSky #EpiSky

PACCARB: www.hhs.gov/ash/advisory...

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.

Of ~125k pts w/ suspected sepsis across 236 U.S. hospitals, only 1 in 5 had broad-spectrum abx (anti-MRSA, anti-PsA) de-escalated by day 4 when no resistant organisms identified. After propensity matching, de-escalation a/w ⬇️ AKI, ICU days, and inpatient mortality. academic.oup.com/cid/advance-...

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

Vaccines work and do not cause autism. I will die on this hill.
These two boys had been exposed to the same smallpox source. The boy without a rash had been vaccinated, the one covered in rash hadn't been vaccinated.
A global vaccination campaign led to eradication of smallpox globally by 1980.

Come and join us! Four (yes 4) new positions as Associate Prof or Professor in @cambridgebiosci.bsky.social‬ in:
-Evolutionary Genomics
-Developmental Plasticity & Robustness
-Infection and/or Immunity
-Molecular & Cellular Biology
Not involved in recruitment (AFAIK), but happy to discuss.