jake
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mediocre-jake.bsky.social
jake
@mediocre-jake.bsky.social
180 followers 450 following 33 posts
Postdoc interested in #ubiquitin #lipid #innateimmunity #E3ligases #endoplasmicreticulum

https://findaresearcher.wehi.edu.au/chua.n

Postdoc (WEHI) https://www.wehi.edu.au/laboratory/feltham-lab/
PhD (UNSW) https://x.com/brownlabunsw?lang=en&mx=
Posts Replies Media Videos
mediocre-jake.bsky.social
Learning more about cryptic interaction areas of CRBN during glue binding presented by Lei Liu from Tsinghua University @tsinghuauniversity.bsky.social

Work partially in a pre-print @biorxivpreprint.bsky.social

#AusUb2025 #LorneUbqiuitin2025
@ausub.bsky.social
November 22, 2025 at 1:28 AM
mediocre-jake.bsky.social
Very nice presentation by Phil Chamberlain from Neomorph to kick off the TPD day today at @ausub.bsky.social #AusUb2025 #LorneUbiquitin2025

From the fundamentals of glues to identifying more in the proteome to glue
November 22, 2025 at 1:22 AM
mediocre-jake.bsky.social
Min Zhuang from ShanghaiTech University talking about the MARCHF5 mitochondria and peroxisome localised E3

#AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social
November 22, 2025 at 1:13 AM
mediocre-jake.bsky.social
@impeiyee.bsky.social from the labs of Sylvie Urbe and Michael Clague presents to us a tale of CTLA4 turnover

Some cool stuff published in
@liverpooluni.bsky.social
@jcb.org

#AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social
November 21, 2025 at 12:47 AM
mediocre-jake.bsky.social
Eric Bennett coming from
@ucsandiego.bsky.social talks about how E3s have plasticity in quality control to facilitate degradation

#AusUb2025 #LorneUbiquitin @ausub.bsky.social
November 21, 2025 at 12:10 AM
mediocre-jake.bsky.social
Always a pleasure to hear about the world of the HECT E3s from @sonjalorenzlab.bsky.social from Max Planck Institute for Multidisciplinary Sciences

Welcome to Australia!

Featuring work published in @cp-molcell.bsky.social @natcomms.nature.com

#LorneUbiquitin2025
#AusUb2025 @ausub.bsky.social
November 20, 2025 at 11:22 PM
mediocre-jake.bsky.social
The unique E2/E3 UBE2O structure presented by Kuen-Phon Wu from Academia Sinica Taiwan

#LorneUbiquitin2025 #AusUb2025 @ausub.bsky.social
November 20, 2025 at 10:44 PM
mediocre-jake.bsky.social
CTLH E3 ligase coming into action with Toxoplasma infection presented by Chris Tonkin

#LorneUbiquitin2025 #Ubiquitin2025 #AusUb2025

@wehi-research.bsky.social
November 20, 2025 at 10:30 PM
mediocre-jake.bsky.social
Day 2 of the conference in Australia

Revisiting the E1-E2-E3 cascade with Chris Lima from the Memorial Sloan Kettering Cancer Center

@ausub.bsky.social

#AusUb2025 #LorneUbiquitin2025
November 20, 2025 at 10:04 PM
mediocre-jake.bsky.social
Sir Philip Cohen presenting on the intersection between glycogen metabolism and ubiquitination

From insulin signaling to glycogen

Really appreciate the historical tour of ubiquitin in innate immunity

@ausub.bsky.social

#ubiquitin #AusUb2025 #LorneUbiquitin2025
November 20, 2025 at 7:01 AM
mediocre-jake.bsky.social
My favorite topic

ER proteins and protein degradation

Yukio Yoshida from Tokyo Metropolitan Institute of Medical Science

Work shown published in @cp-molcell.bsky.social

#AusUb2025 #LorneUbiquitin2025

@ausub.bsky.social
November 20, 2025 at 3:50 AM
mediocre-jake.bsky.social
Fun facts about aryl hydrocarbon receptor presented by @andriigorelik.bsky.social at #AusUb2025 #LorneUbiquitin2025

@ox.ac.uk @ausub.bsky.social
November 20, 2025 at 3:32 AM
mediocre-jake.bsky.social
More and more about E3s

Satpal from MRC Protein Phosphorylation and Ubiquitylation Unit talks about remaining E3s

#AusUb2025 #LorneUbiquitin2025

@ausub.bsky.social
November 20, 2025 at 3:13 AM
mediocre-jake.bsky.social
#AusUb2025
@ausub.bsky.social
Ubiquitin meets mono-ADP-ribosylation = MARUbylation

Presented by @jnpruneda.bsky.social who came all the way to Australia for the #LorneUbiquitin2025 from Oregon Health & Science University

Hopefully the US visitors have a pleasant stay
November 20, 2025 at 2:51 AM
mediocre-jake.bsky.social
Brenda Schulman as the first speaker of #AusUb2025

#LorneUbiquitin2025

Always amazing body of work

@mpibiochem.bsky.social

@ausub.bsky.social
November 20, 2025 at 2:24 AM
mediocre-jake.bsky.social
#AusUb2025 starting off with David Komander kicking off the Lorne Ubiquitin meeting in Australia
@ausub.bsky.social

#ubiquitin
November 20, 2025 at 1:57 AM
mediocre-jake.bsky.social
See you all at Lorne for #AusUb2025

On the bus that departed Melbourne airport with a bunch of delegates from around the world that successfully made ut

@ausub.bsky.social
November 19, 2025 at 11:17 PM
mediocre-jake.bsky.social
📣 First ever international ubiquitin meeting in Australia www.lorneubiquitin.org still accepting abstracts and registrations! Hopefully we can get more people in the Asia-Pacific!
#science #conference #scicomm #Australia
August 7, 2025 at 6:28 AM
mediocre-jake.bsky.social
It's been a wild 3.5 years for Philipp, always a pleasure witnessing Philipp's dedication and his journey in the @komanderlab.bsky.social tackling DUB biology in cancer during his PhD journey here @wehi-research.bsky.social

#ubiquitin #science #PhDlife #PhD
May 9, 2025 at 5:17 AM
mediocre-jake.bsky.social
So nice to see @franciscobustos.bsky.social in person this time as a PI

Nice to catch up and see amazing stuff from your lab

More importantly this person remembered me from a dark background while being online in Australia in 2020 but so ashamed I didn't remember #cshlubiq
April 5, 2025 at 4:22 AM
mediocre-jake.bsky.social
This meeting has a piano performance #cshubiq @cshlmeetings.bsky.social
April 4, 2025 at 10:28 PM
mediocre-jake.bsky.social
A take on the ubiquitin code #cshlubiq @jnpruneda.bsky.social really like the clarity and introduction to this talk
April 2, 2025 at 6:12 PM