mcramel.bsky.social
@mcramel.bsky.social
Reposted
Thrilled to bits to see our latest work online in Dev Cell! 🥳

We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n

tinyurl.com/cell-stretch
Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish
Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...
tinyurl.com
August 6, 2025 at 2:53 PM
Reposted
‘These cracks, they let the developing cells in: A chronicle of trabeculation in the developing zebrafish heart’ 🎵

Theodora Stougiannou highlights recent work from @rashmi-priya.bsky.social & team. #preprint

Check out the #preLight ⬇️ 👀
prelights.biologists.com/highlights/m...
Mechanical fracturing of the extracellular matrix patterns the vertebrate heart - preLights
‘These cracks, They let the Developing Cells in: A Chronicle of Trabeculation in the developing Zebrafish Heart’ -- The authors of this study examine the initiating events that trigger trabecula forma...
prelights.biologists.com
June 9, 2025 at 1:58 PM
Reposted
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
March 10, 2025 at 2:43 AM