Molecular Cell Biology and Immunology Lab
@mcbi-amsumc.bsky.social
Researchers in the Department of Molecular Cell Biology and Immunology (MCBI) perform fundamental and preclinical research in the field of Cancer, Neuro and Mucosal Immunology at the
Amsterdam UMC.
Amsterdam UMC.
On the 1st day of the @cancercenterams.bsky.social annual conference Lotte De Winde presented her recently published data on the development of lymphoma-on-a-chip model to study the role of fibroblasts in this pathology! You can find the publication here doi.org/10.1016/j.mt...
June 19, 2025 at 12:32 PM
On the 1st day of the @cancercenterams.bsky.social annual conference Lotte De Winde presented her recently published data on the development of lymphoma-on-a-chip model to study the role of fibroblasts in this pathology! You can find the publication here doi.org/10.1016/j.mt...
For the next session of our Single Cell club we will host Rosalia Franco Fernandez @amsterdamumc.bsky.social to discuss CD8 responses in gastric cancer metastasis!
March 26, 2025 at 1:00 PM
For the next session of our Single Cell club we will host Rosalia Franco Fernandez @amsterdamumc.bsky.social to discuss CD8 responses in gastric cancer metastasis!
(2) They also potentiated the ability of lymphoma cells to enhance lymphatic vessel permeability, although they did not affect permeability on their own.
February 20, 2025 at 12:15 PM
(2) They also potentiated the ability of lymphoma cells to enhance lymphatic vessel permeability, although they did not affect permeability on their own.
In addition, to survival this model hint at a role of FRCs in contributing to lymphoma cell metastasis in two different ways. (1) They promoted directional migration of lymphoma cells towards the lymphatic vessels.
February 20, 2025 at 12:15 PM
In addition, to survival this model hint at a role of FRCs in contributing to lymphoma cell metastasis in two different ways. (1) They promoted directional migration of lymphoma cells towards the lymphatic vessels.
The addition of primary FRCs in the model improved the viability of the lymphoma cells, which was linked to increased production of interleukin-6, a known survival factor for hematological cancer cells.
February 20, 2025 at 12:15 PM
The addition of primary FRCs in the model improved the viability of the lymphoma cells, which was linked to increased production of interleukin-6, a known survival factor for hematological cancer cells.
They describe the construction of a lymphatic vessel (red) surrounded by lymphoma cells (DLBCL, blue) and primary fibroblastic reticular cells (FRCs, green) in a hydrogel.
February 20, 2025 at 12:15 PM
They describe the construction of a lymphatic vessel (red) surrounded by lymphoma cells (DLBCL, blue) and primary fibroblastic reticular cells (FRCs, green) in a hydrogel.
On the second day of the conference, Eleonora Nardini presented her PhD project aiming at understanding how peptide sialylation affects the adaptive response in hemophilia A. #glycotime
December 13, 2024 at 9:29 AM
On the second day of the conference, Eleonora Nardini presented her PhD project aiming at understanding how peptide sialylation affects the adaptive response in hemophilia A. #glycotime
In the mucosal immunology session Myrthe van Delft presented her research on the novel mice model to study the role of IgA in vivo. The project was performed together with the Lambrecht group @viblifesciences.bsky.social
December 11, 2024 at 3:55 PM
In the mucosal immunology session Myrthe van Delft presented her research on the novel mice model to study the role of IgA in vivo. The project was performed together with the Lambrecht group @viblifesciences.bsky.social
During the keynote, Elga de Vries presented her team’s work on the immune changes associated with the neurodegenerative diseases #MultipleSclerosis and dementia #Alzheimersdisease. Some of the presented results have been discussed there doi.org/10.7554/eLif... rdcu.be/d3b9Q
December 11, 2024 at 3:07 PM
During the keynote, Elga de Vries presented her team’s work on the immune changes associated with the neurodegenerative diseases #MultipleSclerosis and dementia #Alzheimersdisease. Some of the presented results have been discussed there doi.org/10.7554/eLif... rdcu.be/d3b9Q
Today is the beginning of the Dutch Society for Immunology Winterschool! Our department is well represented, starting with Sofía Ibáñez-Molero who presented past and future work on investigating the direct interaction between tumor cells and immune cells!
December 11, 2024 at 11:25 AM
Today is the beginning of the Dutch Society for Immunology Winterschool! Our department is well represented, starting with Sofía Ibáñez-Molero who presented past and future work on investigating the direct interaction between tumor cells and immune cells!