Maximilian von der Linde
@max-vdlinde.bsky.social
Pinned
Our Pavri Lab shows in a new study how B cells organize their DNA during somatic hypermutation, a key step for making protective antibodies after infection or vaccination.
➡️Read the paper: doi.org/10.1016&j.molcel.2025.06.003
➡️Read the paper: doi.org/10.1016&j.molcel.2025.06.003
New Paper!
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵
New Paper!
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵
Our Pavri Lab shows in a new study how B cells organize their DNA during somatic hypermutation, a key step for making protective antibodies after infection or vaccination.
➡️Read the paper: doi.org/10.1016&j.molcel.2025.06.003
➡️Read the paper: doi.org/10.1016&j.molcel.2025.06.003
July 1, 2025 at 7:41 AM
New Paper!
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵
How do human B cells use dynamic DNA topology during antibody maturation? Our research published in Molecular Cell reveals how somatic hypermutation (SHM) and class switch recombination (CSR) work in the context of a regulated multiway 3D chromatin hub. (1/10) 🧵