Maurice Lab
@mauricelab.bsky.social
Exploring the dual nature of signals, particularly Wnt signaling, in homeostasis and cancer using organoids and proteomics to uncover patient-specific mechanisms. Founder of Laigo Bio.
Center for Molecular Medicine | Oncode Institute | madelonmauricelab.nl
Center for Molecular Medicine | Oncode Institute | madelonmauricelab.nl
Jelte van der Vaart, postdoc in our lab, has been awarded an NWO Veni grant! 🎉
He will develop human adrenal organoids to uncover how hormone producing cells change identity and function, shedding light on endocrine health.
We're so proud of his achievement and will support him along the way 😁
He will develop human adrenal organoids to uncover how hormone producing cells change identity and function, shedding light on endocrine health.
We're so proud of his achievement and will support him along the way 😁
August 13, 2025 at 11:40 AM
Jelte van der Vaart, postdoc in our lab, has been awarded an NWO Veni grant! 🎉
He will develop human adrenal organoids to uncover how hormone producing cells change identity and function, shedding light on endocrine health.
We're so proud of his achievement and will support him along the way 😁
He will develop human adrenal organoids to uncover how hormone producing cells change identity and function, shedding light on endocrine health.
We're so proud of his achievement and will support him along the way 😁
Yesterday, @antonvenhuizen.bsky.social successfully defended his thesis "Molecular mechanisms of the
β-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.
We are super proud and wish Dr. Venhuizen all the best in Cambridge!
β-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.
We are super proud and wish Dr. Venhuizen all the best in Cambridge!
May 8, 2025 at 7:39 AM
Yesterday, @antonvenhuizen.bsky.social successfully defended his thesis "Molecular mechanisms of the
β-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.
We are super proud and wish Dr. Venhuizen all the best in Cambridge!
β-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.
We are super proud and wish Dr. Venhuizen all the best in Cambridge!
Reposted by Maurice Lab
Our Center for Molecular Medicine (cmmutrecht.eu) at UMC Utrecht, NL, is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but candidates with a more advanced career are very welcome to apply. shorturl.at/KZeYQ. Please repost!
Center for Molecular Medicine
cmmutrecht.eu
February 7, 2025 at 12:09 PM
Our Center for Molecular Medicine (cmmutrecht.eu) at UMC Utrecht, NL, is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but candidates with a more advanced career are very welcome to apply. shorturl.at/KZeYQ. Please repost!
Want to learn the latest insights on how Wnt signaling controls cell behavior?
Check out a new review by Madelon Maurice (@madelonmaurice.bsky.social) and Stephane Angers at @natrevmcb.bsky.social
Check out a new review by Madelon Maurice (@madelonmaurice.bsky.social) and Stephane Angers at @natrevmcb.bsky.social
✨ New #Review ✨
@madelonmaurice.bsky.social & Stephane Angers discuss the newest insights on #WntSignalling with a focus on biogenesis & transport of Wnts and Wnt receptor complex activation.
👉 go.nature.com/42ynuU0
@madelonmaurice.bsky.social & Stephane Angers discuss the newest insights on #WntSignalling with a focus on biogenesis & transport of Wnts and Wnt receptor complex activation.
👉 go.nature.com/42ynuU0
Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction - Nature Reviews Molecular Cell Biology
Wnt–β-catenin signalling regulates stem cell renewal, development and tissue homeostasis. In this Review, the authors examine recent findings concerning Wnt protein production, receptor activation and...
go.nature.com
January 29, 2025 at 12:21 PM
Want to learn the latest insights on how Wnt signaling controls cell behavior?
Check out a new review by Madelon Maurice (@madelonmaurice.bsky.social) and Stephane Angers at @natrevmcb.bsky.social
Check out a new review by Madelon Maurice (@madelonmaurice.bsky.social) and Stephane Angers at @natrevmcb.bsky.social
Pre-print Alert! 📢
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype
www.biorxiv.org/content/10.1...
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype
www.biorxiv.org/content/10.1...
WNT7B drives a program for pancreatic cancer subtype switching and progression
Hyperactivation of WNT signaling is a well-established hallmark of cancer. Various epithelial cancers express high levels of WNT7B and WNT10A that are not commonly expressed during tissue homeostasis,...
www.biorxiv.org
December 22, 2024 at 8:30 PM
Pre-print Alert! 📢
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype
www.biorxiv.org/content/10.1...
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype
www.biorxiv.org/content/10.1...
🎉 Huge congratulations to Dr. Joep Sprangers! Yesterday, Joep successfully defended his PhD thesis and officially became a doctor! His studies describe the role of WNT7B and WNT10A in regeneration, homeostasis, and cancer.
It was a very special day, couldn’t be prouder.
It was a very special day, couldn’t be prouder.
December 19, 2024 at 11:14 AM
🎉 Huge congratulations to Dr. Joep Sprangers! Yesterday, Joep successfully defended his PhD thesis and officially became a doctor! His studies describe the role of WNT7B and WNT10A in regeneration, homeostasis, and cancer.
It was a very special day, couldn’t be prouder.
It was a very special day, couldn’t be prouder.
Yesterday, our lab turned festive for late Sinterklaas/early Christmas! 🎁 With poems, laughter, and guessing games, we shared stories, gifts, and some surprising personal details. Add drinks, snacks, and a digital fireplace, and it was a night of bonding, cheer, and fun!✨#LifeOutsideTheLab
December 11, 2024 at 11:32 AM
Yesterday, our lab turned festive for late Sinterklaas/early Christmas! 🎁 With poems, laughter, and guessing games, we shared stories, gifts, and some surprising personal details. Add drinks, snacks, and a digital fireplace, and it was a night of bonding, cheer, and fun!✨#LifeOutsideTheLab
Our first post on BlueSky is here 🦋. Great story from @antonvenhuizen.bsky.social from our lab describing the role of AXIN1 mutations in hepatocellular carcinoma. Congrats to Anton for the hard work and the deserved BioRxiv pre-publication! 🥳
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 9, 2024 at 11:53 AM
Our first post on BlueSky is here 🦋. Great story from @antonvenhuizen.bsky.social from our lab describing the role of AXIN1 mutations in hepatocellular carcinoma. Congrats to Anton for the hard work and the deserved BioRxiv pre-publication! 🥳
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...