Matthew McCallum
@mattmccallum.bsky.social
Acting Instructor at UW
Structural biology - Protein design - Microbiology - Virology - Evolution
(he/him)
Structural biology - Protein design - Microbiology - Virology - Evolution
(he/him)
Reposted by Matthew McCallum
With participation of Jimin Lee, Jack Brown, Risako Gen, @dabiophysicist.bsky.social, Cameron Stewart in our lab & in collaboration with the labs of Huan Yan and Tyler Starr
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses
Two coronaviruses related to MERS-CoV, which infect European Pipistrellus bats, have
been found to use ACE2 as their receptor. These viruses target an ACE2 surface region
distant from those recognized...
www.cell.com
February 7, 2025 at 4:12 PM
With participation of Jimin Lee, Jack Brown, Risako Gen, @dabiophysicist.bsky.social, Cameron Stewart in our lab & in collaboration with the labs of Huan Yan and Tyler Starr
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Thanks, and yes that was a surprise. I remain optimistic that these antigens will present more uniquely prefusion epitopes, as it would appear so structurally, and therefore elicit enhanced immunity. In any case, now having an ability to isolate prefusion-specific antibodies will help moving forward
November 17, 2024 at 10:57 PM
Thanks, and yes that was a surprise. I remain optimistic that these antigens will present more uniquely prefusion epitopes, as it would appear so structurally, and therefore elicit enhanced immunity. In any case, now having an ability to isolate prefusion-specific antibodies will help moving forward
I couldn’t have done this work without the incredible mentorship of @veeslerlab.bsky.social
November 17, 2024 at 9:33 PM
I couldn’t have done this work without the incredible mentorship of @veeslerlab.bsky.social