matthieuholub.bsky.social
@matthieuholub.bsky.social
Reposted
CSF testing for suspected neurosyphilis

➡️isolated ocular or otic features: LP not needed

➡️CSF VDRL: specific but not perfectly sensitive
➡️CSF treponemal test: high negative predictive value, for cases with high suspicion despite negative CSF VDRL

doi.org/10.1002/ana....

#IDSky
September 20, 2025 at 3:09 AM
Reposted
🆕🔥State of art review with many🌟s
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...
September 2, 2025 at 2:03 PM
Reposted
Switching to oral therapy has become an option for treating infective endocarditis in select patients. In CID, authors assess its effectiveness in real-life settings, including patients not eligible in current guidelines. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaf452/8237289
Should we extend the use of oral antibiotics in infective endocarditis? The ENDO-ORAL study
This real-life study showed that switching from intravenous to oral antibiotic therapy in infective endocarditis was effective and safe, including in patie
academic.oup.com
August 26, 2025 at 7:17 PM
Reposted
🚨 New Epi Alert this week: Measles and OROV surge in the Americas; chikungunya intensifies esp in Brazil; a cheese-linked outbreak of listeriosis in Europe (18 cases, 2 deaths); cholera crisis in Sudan ongoing ~100k cases, ~2.5k deaths ow.ly/2oCH50WIhwe

#IDSky #clinmicro #MedSky
August 20, 2025 at 2:16 PM
Reposted
Weekly Screening of Circulating Mucorales DNA and early treatment in Severely Burned Patients Improves Survival: Real-Life Bi-center Experience in France

✅ Just Accepted
#IDSky
Weekly Screening of Circulating Mucorales DNA and early treatment in Severely Burned Patients Improves Survival: Real-Life Bi-center Experience in France
Invasive fungal diseases, among which includes invasive wound mucormycosis (IWM), are associated with poor outcomes in severely burned patients (SBP).
doi.org
August 5, 2025 at 11:32 PM