Masahiro Matsuwaka
@matsuepi.bsky.social
PhD student. Study Histone modifications in mouse oocytes and early embryos.
Reposted by Masahiro Matsuwaka
🥂 Congrats to Inoue & co for their new study in our journal (Nature Cell Biology) showing that JARID2-#PRC2 initiates H3K27me2 deposition in the 8-cell-to-morula transition and is also required for subsequent #H3K27me3 deposition at the #blastocyst.
rdcu.be/dZPF5
rdcu.be/dZPF5
H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos
Nature Cell Biology - Matsuwaka et al. show that JARID2-PRC2 initiates H3K27me2 deposition during the eight-cell-to-morula transition, following H2AK119 mono-ubiquitylation deposition. It is also...
rdcu.be
November 16, 2024 at 1:38 PM
🥂 Congrats to Inoue & co for their new study in our journal (Nature Cell Biology) showing that JARID2-#PRC2 initiates H3K27me2 deposition in the 8-cell-to-morula transition and is also required for subsequent #H3K27me3 deposition at the #blastocyst.
rdcu.be/dZPF5
rdcu.be/dZPF5