Mathieu Lupien
@matlupien.bsky.social
Senior scientist @Princess Margaret Cancer Centre, Prof @UofT. BHAG: conquer cancer by treating it as a disease of the chromatin.
Nicely done on the interview. Great to see your work getting the spotlight it deserves! And for those of us looking to dig into the science:
Climate change, age acceleration, and the erosion of fitness in polar bears
Climate change is increasingly disrupting evolved life history strategies and reducing population viability in wild species. Using estimates of epigenetic age acceleration, a cellular biomarker of lif...
www.biorxiv.org
August 6, 2025 at 3:51 AM
Nicely done on the interview. Great to see your work getting the spotlight it deserves! And for those of us looking to dig into the science:
Reposted by Mathieu Lupien
Congratulations to this new generation of leading cancer scientists, and to the message they’re sending, with 50% of the awardees placing epigenetics at the heart of their research. The future is speaking. The path forward is both bright and bold.
July 30, 2025 at 4:18 AM
Congratulations to this new generation of leading cancer scientists, and to the message they’re sending, with 50% of the awardees placing epigenetics at the heart of their research. The future is speaking. The path forward is both bright and bold.
RNA splicing involving poison exons is a whole other world, one I'm all ears to learn about.
July 30, 2025 at 2:21 PM
RNA splicing involving poison exons is a whole other world, one I'm all ears to learn about.
Congratulations to this new generation of leading cancer scientists, and to the message they’re sending, with 50% of the awardees placing epigenetics at the heart of their research. The future is speaking. The path forward is both bright and bold.
July 30, 2025 at 4:18 AM
Congratulations to this new generation of leading cancer scientists, and to the message they’re sending, with 50% of the awardees placing epigenetics at the heart of their research. The future is speaking. The path forward is both bright and bold.
My mindset is more that rather than debating with CIHR about in-person versus virtual reviews, we should unite in pushing for a higher payline.
July 5, 2025 at 4:27 PM
My mindset is more that rather than debating with CIHR about in-person versus virtual reviews, we should unite in pushing for a higher payline.
Raising the payline seems better than IP meetings to improve grant review. At current levels, reviewers culture is shifted on picking one top grant from 8–10. A 25–30% payline shifts the focus to ranking the top ~3, forcing clearer justification of rank order to exclude grant 4,5 and 6.
July 4, 2025 at 9:33 PM
Raising the payline seems better than IP meetings to improve grant review. At current levels, reviewers culture is shifted on picking one top grant from 8–10. A 25–30% payline shifts the focus to ranking the top ~3, forcing clearer justification of rank order to exclude grant 4,5 and 6.