How do bottlenecks affect mutant takeover in spatial metapopulations?

Our pre-print reveals that bottleneck strength, frequency, and cell migration intricately drive fixation and extinction - even leading to interesting non-monotonic behaviour.

Check it out: doi.org/10.48550/arXiv.2504.08433

Had a great time at the @physicsoflifeuk.bsky.social conference in Harrogate this year! Really fantastic to see all the good work ongoing and the community thriving, particularly the ECR part 😄

Found a lovely copy of "On the Origin of Species" over the break. Surprisingly entertaining to read with a modern evolutionary biology perspective! Absolutely nails certain points despite no knowledge of genetics. Can't believe I hadn't tried reading it sooner.

Just another part of the mass exodus here starting anew and looking for my people!

I'm Matthew, a PhD student at Leeds working on eco-evolutionary models of biology, particularly regarding AMR and cancer.

I play & watch football, run, and paint Warhammer. Also, Darwin and I are best buds.