@martin-belmontef.bsky.social
Congrats!!
Really happy with this spotlight about our recent publication! Check also this spotlight on @jcb.org
Klein and Overholtzer @mskcancercenter.bsky.social discuss new findings from the Deretic group (@thabataduque.bsky.social et al. rupress.org/jcb/article/...) showing ATG16L, a regulator of lysosomal stress responses, has a day job regulating the v-ATPase. rupress.org/jcb/article/...
September 17, 2025 at 3:27 PM
Congrats!!
🚨 New paper out!
Neonatal enterocytes rely on autophagy & mitophagy to sustain nutrient absorption. Our study demonstrates that the mitochondria–lysosome axis controls the weaning transition and may contribute to childhood malnutrition.
👉https://www.biorxiv.org/content/10.1101/2025.09.09.674148v3
Neonatal enterocytes rely on autophagy & mitophagy to sustain nutrient absorption. Our study demonstrates that the mitochondria–lysosome axis controls the weaning transition and may contribute to childhood malnutrition.
👉https://www.biorxiv.org/content/10.1101/2025.09.09.674148v3
September 16, 2025 at 9:44 AM
🚨 New paper out!
Neonatal enterocytes rely on autophagy & mitophagy to sustain nutrient absorption. Our study demonstrates that the mitochondria–lysosome axis controls the weaning transition and may contribute to childhood malnutrition.
👉https://www.biorxiv.org/content/10.1101/2025.09.09.674148v3
Neonatal enterocytes rely on autophagy & mitophagy to sustain nutrient absorption. Our study demonstrates that the mitochondria–lysosome axis controls the weaning transition and may contribute to childhood malnutrition.
👉https://www.biorxiv.org/content/10.1101/2025.09.09.674148v3
🧪 Canonical autophagy isn’t enough! In our new study, only CASM can coordinate the membrane remodeling needed to build a single lumen in tubes. Read how CASM drives endocytic recycling to drive morphogenesis www.biorxiv.org/content/10.1...
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
April 29, 2025 at 7:43 AM
🧪 Canonical autophagy isn’t enough! In our new study, only CASM can coordinate the membrane remodeling needed to build a single lumen in tubes. Read how CASM drives endocytic recycling to drive morphogenesis www.biorxiv.org/content/10.1...
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
#ScienceTwitter #Autophagy #Morphogenesis #CellPolarity
🚨 New paper out! We reveal that noncanonical autophagy (CASM) is a critical driver of epithelial lumen formation. CASM regulates endocytic recycling and membrane remodeling—without it, cells can’t resolve into a single lumen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
April 29, 2025 at 7:37 AM
🚨 New paper out! We reveal that noncanonical autophagy (CASM) is a critical driver of epithelial lumen formation. CASM regulates endocytic recycling and membrane remodeling—without it, cells can’t resolve into a single lumen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...