Marta Porniece
@martaapp.bsky.social
🇱🇻🇩🇪🇺🇸 #WalterBenjamin Postdoc @bostonchildrens.bsky.social, @bidmcreseach.bsky.social, @harvardmed.bsky.social,
alumni of @mpi-metabolism.bsky.social, Non-neuronal cells, hormones, obesity. Into 🏃🏻♀️🍦🍓
alumni of @mpi-metabolism.bsky.social, Non-neuronal cells, hormones, obesity. Into 🏃🏻♀️🍦🍓
1️⃣
🥳 Thrilled to share that my postdoc work has finally hit the press!
www.nature.com/articles/s41...
When we started, we didn’t really know what PVH-MC4R neurons do in obesity.
Are they still signaling or “dead”? (e.g., does the chronically high leptin alter α-MSH–MC4R signaling?)
🧵👇
🥳 Thrilled to share that my postdoc work has finally hit the press!
www.nature.com/articles/s41...
When we started, we didn’t really know what PVH-MC4R neurons do in obesity.
Are they still signaling or “dead”? (e.g., does the chronically high leptin alter α-MSH–MC4R signaling?)
🧵👇
Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons - Scientific Reports
Scientific Reports - Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons
www.nature.com
October 15, 2025 at 4:52 PM
1️⃣
🥳 Thrilled to share that my postdoc work has finally hit the press!
www.nature.com/articles/s41...
When we started, we didn’t really know what PVH-MC4R neurons do in obesity.
Are they still signaling or “dead”? (e.g., does the chronically high leptin alter α-MSH–MC4R signaling?)
🧵👇
🥳 Thrilled to share that my postdoc work has finally hit the press!
www.nature.com/articles/s41...
When we started, we didn’t really know what PVH-MC4R neurons do in obesity.
Are they still signaling or “dead”? (e.g., does the chronically high leptin alter α-MSH–MC4R signaling?)
🧵👇
Reposted by Marta Porniece
Exciting news from @sophiesteculorum.bsky.social Lab!🤓
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
www.nature.com
June 11, 2025 at 3:06 PM
Exciting news from @sophiesteculorum.bsky.social Lab!🤓
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
Reposted by Marta Porniece
I am excited to share our preprint on how hypothalamic dopamine neurons govern slow changes in motivation over days! Below are our findings:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days
The rise and fall of motivational states may take place over timescales as long as many days. We used mouse mating behavior to model how the brain orchestrates slow-timescale changes in motivation. Ma...
www.biorxiv.org
June 2, 2025 at 6:25 PM
I am excited to share our preprint on how hypothalamic dopamine neurons govern slow changes in motivation over days! Below are our findings:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
🚨 Paper alert!
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons
Melanocortin-4 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus (PVHMC4R) integrate hunger-promoting and hunger-suppressing signals to regulate satiety. Food consumption-...
www.biorxiv.org
May 28, 2025 at 8:28 PM
🚨 Paper alert!
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience