Dr. Jules Marien
@marienj.bsky.social
PhD in biophysics/biochemistry working on the interaction between the phosphorylated Tau protein and microtubules. Molecular dynamist. Tamer of IDRs and IDPs since 2022
(They/Them)
https://scholar.google.com/citations?user=4S1QUPgAAAAJ&hl=fr
(They/Them)
https://scholar.google.com/citations?user=4S1QUPgAAAAJ&hl=fr
- The "paperclip" model of Tau can be retrieved and refined by defining a "statistical tertiary organisation" with a bit of polymer physics
July 25, 2025 at 7:03 AM
- The "paperclip" model of Tau can be retrieved and refined by defining a "statistical tertiary organisation" with a bit of polymer physics
- Flexibility and curvature patterns in the repeat domains hint at a possible functional role of local disorder variations
July 25, 2025 at 7:01 AM
- Flexibility and curvature patterns in the repeat domains hint at a possible functional role of local disorder variations
A few fun results :
- an exciting correlation between T2 experimental relaxation times and the newly-developed LF metrics, which geometrically quantifies local flexibility of the backbone
- an exciting correlation between T2 experimental relaxation times and the newly-developed LF metrics, which geometrically quantifies local flexibility of the backbone
July 25, 2025 at 7:00 AM
A few fun results :
- an exciting correlation between T2 experimental relaxation times and the newly-developed LF metrics, which geometrically quantifies local flexibility of the backbone
- an exciting correlation between T2 experimental relaxation times and the newly-developed LF metrics, which geometrically quantifies local flexibility of the backbone