marielkleer.bsky.social
@marielkleer.bsky.social
Reposted
A plea from a humble virologist.
Worried about my team.
Annoyed by interference from @dalhousie.bsky.social leadership.
LOCKED OUT!
@dalfaculty.bsky.social
#KeepDalStrong
August 29, 2025 at 5:39 PM
Reposted
Our newest work reveals that SARS-CoV-2 evolved to produce a truncated version of its N protein to antagonize antiviral responses. This 'mini' N, called N*M210, sequesters dsRNA, blocks interferon activation, defeats RNaseL & disassembles stress granules and p-bodies. www.biorxiv.org/content/10.1...
A truncated SARS-CoV-2 nucleocapsid protein enhances virus fitness by evading antiviral responses
Viruses face a selective pressure to evade cellular antiviral responses to control the outcome of an infection. However, due to their limited genome size, viruses must adopt unique strategies to confr...
www.biorxiv.org
February 27, 2025 at 3:35 AM