Big picture: better stories should follow better evidence, not the other way around.
Read the piece & join the discussion:
authors.elsevier.com/a/1lt2w5Eb1B...
#TrendsMolMed #redox #evidence

The need for greater precision in redox biology has been recognized. To break free from the ‘indiscriminate antioxidant use age’ in society & from the ‘command of publicly approved science’ in research, repurposing of the oxidative stress narrative is warranted
#oxidative_stress

Oxidative stress isn’t just “bad”. Reactive species can be essential signaling molecules - context, dose, timing, and location matter.
Yet we still lack clinical thresholds to define conditions like eustress vs distress.
#RedoxSignaling #antioxidants

Early, catchy narratives spread fast, then resist correction, especially once industry, media, and public expectations lock them in.
This science↔society loop can stall progress.
#Narratives #MolecularMedicine #SciSoc

There's a nice discussion at Frank Harrell's datamethods:

discourse.datamethods.org/t/dichotomiz...

Hats off to them for publishing that paper without mentioning n-of-1 trials or person-by-treatment interactions 😬. We've this paper currently under review. It's frustratingly long-winded, but that's the complex nature of the precision nutrition beast I suppose, osf.io/preprints/os...