Margaret Lam
@margaretlam.bsky.social
Research Fellow at Monash University - microbial genomics, Klebsiella, Acinetobacter, plasmids
Reposted by Margaret Lam
Huge preprint if you are interested in bacterial strain taxonomy! The why and how of cgMLST LIN codes: An extensively revised and expanded version doi.org/10.1101/2024... I will summarize it for you in this thread 👇
Life Identification Numbers: A bacterial strain nomenclature approach
Unified strain taxonomies are needed for the epidemiological surveillance of bacterial pathogens and international communication in microbiological research. Core genome multilocus sequence typing (cg...
doi.org
November 30, 2025 at 7:51 PM
Huge preprint if you are interested in bacterial strain taxonomy! The why and how of cgMLST LIN codes: An extensively revised and expanded version doi.org/10.1101/2024... I will summarize it for you in this thread 👇
Reposted by Margaret Lam
Thrilled to share this preprint on Klebsiella pneumoniae plasmids in a One Health setting 🦠 Fantastic work by @twinkler.bsky.social! 🎉 @irenlohr.bsky.social @margaretlam.bsky.social
A One Health study of Klebsiella pneumoniae species complex plasmids shows a highly diverse and ecologically adaptable plasmidome https://www.biorxiv.org/content/10.1101/2025.09.14.676155v1
September 16, 2025 at 9:40 AM
Thrilled to share this preprint on Klebsiella pneumoniae plasmids in a One Health setting 🦠 Fantastic work by @twinkler.bsky.social! 🎉 @irenlohr.bsky.social @margaretlam.bsky.social
Reposted by Margaret Lam
I want to thank all of my fantastic collaborators their help and support with this work @codendall.bsky.social @neisseriaspanin.bsky.social @margaretlam.bsky.social @katholt.bsky.social @josebengoechea.bsky.social (+ many others not on bluesky)
September 15, 2025 at 9:54 AM
I want to thank all of my fantastic collaborators their help and support with this work @codendall.bsky.social @neisseriaspanin.bsky.social @margaretlam.bsky.social @katholt.bsky.social @josebengoechea.bsky.social (+ many others not on bluesky)
Reposted by Margaret Lam
Pleased to say that our preprint benchmarking Nanopore data for MLST, cgMLST, cgSNP & AMR typing from bacterial isolates is out! TL;DR you can get almost perfect results from 50x depth using live SUP basecalling with a GPU in under 20 hours #microsky#IDsky 🦠🧬🖥️ /1
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
July 30, 2025 at 2:11 AM
Pleased to say that our preprint benchmarking Nanopore data for MLST, cgMLST, cgSNP & AMR typing from bacterial isolates is out! TL;DR you can get almost perfect results from 50x depth using live SUP basecalling with a GPU in under 20 hours #microsky#IDsky 🦠🧬🖥️ /1
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Margaret Lam
New preprint where we analysed IS loads in 🦠 #Klebsiella pneumoniae lineages and found they're inversely associated with nutrient usage. We propose an insertional tolerance model, whereby IS can only insert into metabolically-tolerable sites.
#IDSky #MicroSky 🧪
www.biorxiv.org/content/10.1...
#IDSky #MicroSky 🧪
www.biorxiv.org/content/10.1...
July 29, 2025 at 2:29 AM
New preprint where we analysed IS loads in 🦠 #Klebsiella pneumoniae lineages and found they're inversely associated with nutrient usage. We propose an insertional tolerance model, whereby IS can only insert into metabolically-tolerable sites.
#IDSky #MicroSky 🧪
www.biorxiv.org/content/10.1...
#IDSky #MicroSky 🧪
www.biorxiv.org/content/10.1...
Reposted by Margaret Lam
We are pleased to launch the KlebNET Genomic Epidemiology Consortium!
We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones.
Join us here:
klebnet.org/klebnet-gsp-...
#ABPHM25
We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones.
Join us here:
klebnet.org/klebnet-gsp-...
#ABPHM25
KlebNET-GSP
klebnet.org
May 21, 2025 at 12:40 PM
We are pleased to launch the KlebNET Genomic Epidemiology Consortium!
We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones.
Join us here:
klebnet.org/klebnet-gsp-...
#ABPHM25
We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones.
Join us here:
klebnet.org/klebnet-gsp-...
#ABPHM25