Marton Czikkely
marczikkely.bsky.social
Marton Czikkely
@marczikkely.bsky.social
Reposted by Marton Czikkely
🚨 Our latest research in @naturecomms.bsky.social shows a promising strategy for less resistance-prone #antibiotics. For details, see the thread below and read the paper “Exploring the principles behind antibiotics with limited resistance” here: #MEvoSky www.nature.com/articles/s41...
Exploring the principles behind antibiotics with limited resistance - Nature Communications
This study shows that only those dual-targeting antibiotics limit resistance in Gram-negative pathogens that also target the membrane of the bacteria. This mechanism provides a basis for designing fut...
www.nature.com
February 24, 2025 at 11:09 AM
Reposted by Marton Czikkely
For a similar study on Gram-positive bacteria, check out our previous thread: bsky.app/profile/csab...
Thrilled to share our latest work, "Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance" in Science Translational Medicine! For details, see the thread below and read the paper here: www.science.org/doi/10.1126/...
Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance
Antibiotic candidates induce multidrug resistance in Staphylococcus aureus without compromising bacterial viability.
www.science.org
January 13, 2025 at 4:30 PM
Reposted by Marton Czikkely
💊🦠OUT NOW - comprehensive analysis of the propensity of ESKAPE pathogens to evolve resistance to new and in development antibiotics by Csaba Pal, Balint Kintses, Balazs Papp and colleagues. Dive in here...
www.nature.com/articles/s41...
ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro - Nature Microbiology
An extensive experimental analysis of resistance to antibiotics in development or introduced post-2017 in ESKAPE bacteria reveals the dynamics of resistance acquisition, mutational targets and the pre...
www.nature.com
January 13, 2025 at 1:57 PM