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Glioblastomas (GBMs) are the most common and aggressive malignant brain tumors, presenting significant challenges for treatment due to their invasive nature and localization in critical brain regions. Standard treatment includes surgical resection followed by radiation and adjuvant chemotherapy with temozolomide (TMZ). Recent advances in immunotherapy, including the use of mRNA vaccines, offer promising alternatives. This review focuses on the emerging use of mRNA vaccines for GBM treatment. We summarize recent advancements, evaluate current obstacles, and discuss notable successes in this field. Our analysis highlights that while mRNA vaccines have shown potential, their use in GBM treatment is still experimental. Ongoing research and clinical trials are essential to fully understand their therapeutic potential. Future developments in mRNA vaccine technology and insights into GBM-specific immune responses may lead to more targeted and effective treatments. Despite the promise, further research is crucial to validate and optimize the effectiveness of mRNA vaccines in combating GBM. Graphical Abstract

Ultrasound has long been used for helping doctors see inside the body, but focused high frequency sound waves are offering new ways of targeting cancer.

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One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

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Asal v Elias Egyptian Open 2025: Report from the final of the 2025 PSA Squash Tour Egyptian Open Final between Asal and Elias.

It crucially also reveals promising genetic targets for potential control.

Egyptian Open Gohar v El Hammamy: Report from the PSA Squash Tour 2025 CIB Egyptian Open semi-final - Nouran Gohar v Hania El Hammamy

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CIB Egyptian Open: Report and reaction from the quarter-finals of the 2025 CIB Egyptian Open at the Great Pyramids of Giza.

A refined type of spectroscopy could advance a long-standing debate about the presence of dinosaur soft tissue

Since its discovery, astronomers have been frantically trying to gather as much information as they can about the newest interstellar interloper dubbed 3I/ATLAS. It's been challenging, but they've got...