Mansi Srivastava
@mansi-srivastava.bsky.social
she/her, Neuroscience buff, PhD scholar @ Laboratory of Chromatin Biology and Epigenetics, SNIoE
#epigenetics #neuroepigenetics
#epigenetics #neuroepigenetics
Reposted by Mansi Srivastava
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine
@ulrikakmarklund.bsky.social
www.nature.com/articles/s41...
@ulrikakmarklund.bsky.social
www.nature.com/articles/s41...
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine - Nature Neuroscience
The neuronal composition of the intestinal submucosal plexus is incompletely understood. Here Li et al. define their neuron classes, connectome and stepwise acquisition of identities.
www.nature.com
June 4, 2025 at 3:15 PM
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine
@ulrikakmarklund.bsky.social
www.nature.com/articles/s41...
@ulrikakmarklund.bsky.social
www.nature.com/articles/s41...
Reposted by Mansi Srivastava
Neuronal aging leads to widespread dysregulation of RNA biology, including mislocalization of splicing proteins like TDP-43, chronic cellular stress, and reduced resiliency
@kevinrhine.bsky.social
www.nature.com/articles/s41...
@kevinrhine.bsky.social
www.nature.com/articles/s41...
Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress - Nature Neuroscience
Rhine et al. find that neuronal aging leads to widespread dysregulation of RNA biology, including mislocalization of splicing proteins like TDP-43, chronic cellular stress and reduced resiliency.
www.nature.com
June 6, 2025 at 5:10 PM
Neuronal aging leads to widespread dysregulation of RNA biology, including mislocalization of splicing proteins like TDP-43, chronic cellular stress, and reduced resiliency
@kevinrhine.bsky.social
www.nature.com/articles/s41...
@kevinrhine.bsky.social
www.nature.com/articles/s41...
Reposted by Mansi Srivastava
Online now:
Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
(Neuron 111, 1191–1204.e1–e5; April 19, 2023)
dlvr.it
May 28, 2025 at 3:23 PM
Online now:
Reposted by Mansi Srivastava
Applications for the Trainee Professional Development Award are now open!
If you have submitted an abstract for #SfN25, you may be eligible to receive complimentary registration and a travel stipend!
Submit your application by June 24, 5 p.m. EDT.
🔗 bit.ly/4dWku7h
#NeuroSky #AcademicChatter
If you have submitted an abstract for #SfN25, you may be eligible to receive complimentary registration and a travel stipend!
Submit your application by June 24, 5 p.m. EDT.
🔗 bit.ly/4dWku7h
#NeuroSky #AcademicChatter
June 10, 2025 at 2:00 PM
Applications for the Trainee Professional Development Award are now open!
If you have submitted an abstract for #SfN25, you may be eligible to receive complimentary registration and a travel stipend!
Submit your application by June 24, 5 p.m. EDT.
🔗 bit.ly/4dWku7h
#NeuroSky #AcademicChatter
If you have submitted an abstract for #SfN25, you may be eligible to receive complimentary registration and a travel stipend!
Submit your application by June 24, 5 p.m. EDT.
🔗 bit.ly/4dWku7h
#NeuroSky #AcademicChatter
Reposted by Mansi Srivastava
Excited to share the latest preprint spearheaded by @ankitasharma.bsky.social We show that SP1 works with the #Wnt signalling pathway to drive cell growth in colon development and cancer. Cross-species analysis confirmed this role is conserved, suggesting potential for dual targeting in CRC therapy.
SP1 amplifies the effects of cellular proliferation via the Wnt/β-catenin pathway in colon development and cancer https://www.biorxiv.org/content/10.1101/2025.06.05.658012v1
June 11, 2025 at 12:37 PM
Excited to share the latest preprint spearheaded by @ankitasharma.bsky.social We show that SP1 works with the #Wnt signalling pathway to drive cell growth in colon development and cancer. Cross-species analysis confirmed this role is conserved, suggesting potential for dual targeting in CRC therapy.