Amanda Collier
@mandy-collier.bsky.social
Postdoc fellow in the Plath lab at UCLA | Alum Cambridge University & Babraham Institute | Researching epigenetic changes during human embryonic development 🇬🇧🏳️🌈
Reposted by Amanda Collier
Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com
@natcellbio.nature.com
α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology
Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...
rb.gy
April 24, 2025 at 6:57 AM
Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com
@natcellbio.nature.com
Reposted by Amanda Collier
Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA.
Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...
Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...
RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry
Mammalian cells present RNA-binding proteins on the cell surface that form clustered
domains containing glycoRNAs.
www.cell.com
February 27, 2025 at 3:48 PM
Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA.
Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...
Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...
Reposted by Amanda Collier
Delighted to share our paper where we describe the “Generalization of the sci-L3 method to achieve high-throughput linear amplification for replication template strand sequencing, genome conformation capture, and the joint profiling of RNA and chromatin accessibility”.
February 25, 2025 at 10:37 PM
Delighted to share our paper where we describe the “Generalization of the sci-L3 method to achieve high-throughput linear amplification for replication template strand sequencing, genome conformation capture, and the joint profiling of RNA and chromatin accessibility”.
Reposted by Amanda Collier
Try our Early embryogenesis prediction tool. Hopefully it will be useful for the community to benchmark and explore embryo model data. I have found it very useful when reviewing manuscript with such datasets. Just upload and in a few minutes 😁
petropoulos-lanner-labs.clintec.ki.se
petropoulos-lanner-labs.clintec.ki.se
Petropoulos & Lanner Labs (Homepage)
petropoulos-lanner-labs.clintec.ki.se
November 17, 2024 at 9:36 AM
Try our Early embryogenesis prediction tool. Hopefully it will be useful for the community to benchmark and explore embryo model data. I have found it very useful when reviewing manuscript with such datasets. Just upload and in a few minutes 😁
petropoulos-lanner-labs.clintec.ki.se
petropoulos-lanner-labs.clintec.ki.se
Reposted by Amanda Collier
Couldn’t find a dedicated stem cell biology starter pack, so started one here: go.bsky.app/UTW4d7b
Feel free to repost/share and let me know if you would like to be added. #stemcell #pluripotency
Feel free to repost/share and let me know if you would like to be added. #stemcell #pluripotency
November 11, 2024 at 9:09 PM
Couldn’t find a dedicated stem cell biology starter pack, so started one here: go.bsky.app/UTW4d7b
Feel free to repost/share and let me know if you would like to be added. #stemcell #pluripotency
Feel free to repost/share and let me know if you would like to be added. #stemcell #pluripotency
Reposted by Amanda Collier
November 9, 2024 at 11:49 PM