Maine-Anjou AAV-GN Research Group
@maineanjoureg.bsky.social
The Maine-Anjou Research Group is a multicenter French team focusing on #ANCA associated #vasculitis with #glomerulonephritis. Posts by @benoitbrilland.bsky.social
How to reconciliate these findings? SGLT2i likely protect kidneys in chronic or pre-flare phases (anti-fibrotic, podocyte-protective) but not during active autoimmune inflammation. We still need to target the immune system...
November 7, 2025 at 3:10 PM
How to reconciliate these findings? SGLT2i likely protect kidneys in chronic or pre-flare phases (anti-fibrotic, podocyte-protective) but not during active autoimmune inflammation. We still need to target the immune system...
Link to study: www.nature.com/articles/s41...
Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis - Nature Communications
The etiology of autoimmune disease anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is still poorly understood. Here the authors associate anti-myeloperoxidase (MPO) IgM-express...
www.nature.com
April 1, 2025 at 12:49 PM
Link to study: www.nature.com/articles/s41...
1️⃣ Biomarker: IgM levels could signal early disease activity (relapse prediction?).
2️⃣ Therapeutic: new strategies may focus on eliminating autoreactive IgM B cells (CAR-T?).
3️⃣ Mechanistic: uncovering IgM’s role offers clues to triggers of autoreactivity and flares.
2️⃣ Therapeutic: new strategies may focus on eliminating autoreactive IgM B cells (CAR-T?).
3️⃣ Mechanistic: uncovering IgM’s role offers clues to triggers of autoreactivity and flares.
April 1, 2025 at 12:49 PM
1️⃣ Biomarker: IgM levels could signal early disease activity (relapse prediction?).
2️⃣ Therapeutic: new strategies may focus on eliminating autoreactive IgM B cells (CAR-T?).
3️⃣ Mechanistic: uncovering IgM’s role offers clues to triggers of autoreactivity and flares.
2️⃣ Therapeutic: new strategies may focus on eliminating autoreactive IgM B cells (CAR-T?).
3️⃣ Mechanistic: uncovering IgM’s role offers clues to triggers of autoreactivity and flares.