Madeleine L Ball
@madeleinelball.bsky.social
Flyentist working on understanding supracellular cables during embryo development in Cambridge. Fan of super-res microscopy, lover of books, and appreciator of bugs. 🔬📚🦗
https://orcid.org/0000-0002-6150-0485
https://orcid.org/0000-0002-6150-0485
Great to see this published! Amazing work 😄🔬
Delighted to see my PhD work finally published! Here we used the amazingly versatile Drosophila model system to uncover mechanisms behind the rare renal disorder Dent's disease. Have a read over at: www.kidney-international.org/article/S008...
A Drosophila model for Dent’s disease type 1 revealed impaired endoplasmic reticulum export of Cubilin as pathogenic mechanism
Mutations in the CLCN5 gene encoding the chloride-hydrogen exchanger ClC-5 cause Dent’s
disease type 1, a genetic disorder of the endolysosomal pathway in the proximal tubules
of the kidneys. A hallma...
www.kidney-international.org
February 12, 2026 at 5:11 PM
Great to see this published! Amazing work 😄🔬
Stunning work!
🚨Preprint alert🚨 How does chromatin “architecture” form at CTCF sites? Our new preprint with @voslab.org and @andersshansen.bsky.social shows CTCF dimerization promotes nucleosome oligomerization on chromatin. tinyurl.com/CTCF-nucleos...
February 12, 2026 at 11:38 AM
Stunning work!
Made a bluesky account especially for this - our new spotlight on a really interesting new paper is now available to read! Findings that go against what "should" be based on current knowledge are always some of my favourite discussions to have, one of the great joys of being in Biology. 🧬
Spotlight: Ball and Röper @pdncambridge.bsky.social discuss recent findings by Almasoud, Franz et al. (rupress.org/jcb/article/...) describing how apical–basal polarity regulates cell–cell adhesion in the #Drosophila fat body. rupress.org/jcb/article/...
#Adhesion #Cytoskeleton #Development
#Adhesion #Cytoskeleton #Development
February 12, 2026 at 9:43 AM
Made a bluesky account especially for this - our new spotlight on a really interesting new paper is now available to read! Findings that go against what "should" be based on current knowledge are always some of my favourite discussions to have, one of the great joys of being in Biology. 🧬