Maddalena Staiano
maddalenastn.bsky.social
Maddalena Staiano
@maddalenastn.bsky.social
PhD Student at @biozentrum.unibas.ch - Systems Biology - Physics of Complex Systems
Reposted by Maddalena Staiano
Super excited that our group will be supported by an ERC Starting Grant!

In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.

We'll have PhD and Postdoc positions available, please get in touch if interested!
September 4, 2025 at 11:27 AM
Reposted by Maddalena Staiano
Our paper is on the cover of @cp-devcell.bsky.social . Image: embryonic murine salivary-gland explants stained for fate determinants; p63 (cyan) and HES1 (yellow). Thanks to everyone involved.
doi.org/10.1016/j.de...
October 6, 2025 at 7:38 PM
Reposted by Maddalena Staiano
How can we quantify cell potency from scRNAseq data?
In our latest preprint, we show that intrinsic dimensionality (ID) tracks potency in single cells across reprogramming datasets, and we provide IDEAS, a Python toolkit for ID-based potency analysis: www.biorxiv.org/content/10.1...
Intrinsic dimensionality of single-cell transcriptomic data reveals potency landscapes during cell reprogramming
Cell potency, the ability of a cell to generate other cell types, is a fundamental property that drives development, regeneration, and reprogramming. Recent computational advances have en- abled estim...
www.biorxiv.org
July 25, 2025 at 7:46 PM