Matteo Castelli
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macastelli.bsky.social
Matteo Castelli
@macastelli.bsky.social
Post-doctoral research scholar | Rommie Amaro's lab - UCSanDiego

Computational chemist.
Reposted by Matteo Castelli
I have a PhD position available in my lab at the University of Freiburg!! If you, or someone you know, might be looking for a position using modeling and simulations to uncover secrets in (glyco-)protein structure/function relationships please take a look at our website!
www.kearnslab.org
October 17, 2025 at 8:21 PM
Reposted by Matteo Castelli
🚀New adventures in #DrugDiscovery: We designed multi-target leads that hit Hsp70, Hsp90 & Cdc37 at once—disrupting chaperone networks that fuel tumor growth. 🧬💥 Great collaboration with Mollapour @medmol.bsky.social and Gestwicki Labs
#CancerResearch #CompChem

shorturl.at/gGk7m
Design of multi-target peptide modulators for protein chaperone networks
Essential chaperones heat shock protein 70 (Hsp70) and heat shock protein 90 (Hsp90) collaborate in oncoprotein folding. Dual inhibition of these chap…
www.sciencedirect.com
August 26, 2025 at 9:31 AM
Reposted by Matteo Castelli
✨✨ It's #glycotime for #HIV Env ✨✨

N-linked glycans modulate flexibility & MPER epitope exposure #glycotime

Huge effort by @shehata92.bsky.social @lcasalino88.bsky.social with cryoET of Env in VLPs by @thevillalab.bsky.social & team 💪

Would love feedback!

www.biorxiv.org/content/10.1...
March 28, 2025 at 4:23 AM