Michael O’Brien
m0bri3n.bsky.social
Michael O’Brien
@m0bri3n.bsky.social
phd student @ harvard. microtubules + molecular motors and cryo-EM informed biophysical modeling. silly person presenting serious 🥸
a toy demonstration: in only a few blocks of code, we can use cryoJAX and JAX automatic differentiation to implement a gradient-based optimization that recovers conformation A starting from conformation B. check out the code (roughly) used here: michael-0brien.github.io/cryojax/exam...
November 14, 2025 at 5:37 PM