Lynn Tan
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lynnxtan.bsky.social
Lynn Tan
@lynnxtan.bsky.social
biochemist | #crystallography lab rat @WEHI_research | aspiring dog whisperer | color-coded list enthusiast | she/her 🔬🧪🧬🦠🎨🎮
Reposted by Lynn Tan
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗

🦟 Transgenic parasites without Pfs230 D13D14 do not transmit

🦙 💉Nanobodies + mRNA induced antibodies reduce transmission

New in @Science.org

www.science.org/doi/10.1126/...

#ScienceResearch #Malaria #WEHI
August 1, 2025 at 12:58 AM
Reposted by Lynn Tan
Stabilized PvRBP2b variants - wonderful collab with Sarel Fleishman

🔥Increased yields and thermal stability

✌️Maintains human mAb recognition

🩸Sensitivity as a sero-diagnostic for P. vivax

💕 Editors Pick

👨🏻‍🔬First paper for PhD student Jaison

Please read & repost!

www.jbc.org/article/S002...
Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax
Plasmodium vivax is emerging as the most prevalent species causing malaria outside Africa. Most P. vivax infections are relapses due to the reactivation of the dormant liver stage parasites (hypnozoit...
www.jbc.org
March 6, 2025 at 4:51 AM