@parse.bsky.social released an amazing 10M cell dataset for immunologists: they profiled 90 cytokine responses in 12 donors with the GigaLab platform:
www.parsebiosciences.com/datasets/10-...

We have recently uploaded our revised manuscript “Evaluating the role of pre-training dataset size and diversity on single-cell foundation model performance”.

TL;DR: More models, more tasks => same results.

Looking forward to Cytokines 2025! @alleninstitute.org will be there, with posters about plasma cells, Rheumatoid arthritis, neuroimmune signaling, ulcerative colitis, TRM formation, and a new interferon signaling atlas.

Times and details at:
apps.allenimmunology.org/aifi/present...

#cytokines2025

As we continue to develop the @alleninstitute.org Allen Institute for Immunology web platform, our first big challenge was to build tools to support the release of the amazing longitudinal Immune Health study, published yesterday in Nature:
www.nature.com/articles/s41...

Years before the pain begins, early-warning signs for rheumatoid arthritis (RA) could help doctors catch the disease before it starts. 🧵

Two #AACR25 posters from Allen Institute for Immunology will be up Tuesday from 9-12.

Medbh Dillon will showcase 3D Multiple Myeloma culture models at Sec. 6, No. 14

Imran McGrath and I have our scRNA-seq and spatial transcriptomics from MM patients at Sec. 28 No. 11

@alleninstitute.bsky.social

The Allen Institute for Immunology is at #AACR25 conference!

Come see my poster to preview our open data and tools for Multiple Myeloma.

2 PM, Section 46, Board 11

More details and where to find us at tinyurl.com/allen-aacr-2...

@alleninstitute.bsky.social @theaacr.bsky.social

🩸🔬 Introducing #CryoSCAPE, a groundbreaking technique that keeps blood cells alive in deep freeze. This innovation promises to expand the reach of cutting-edge single-cell technologies to rural or underserved populations. ✨ 🧵

#SingleCellTech #RNAseq

Amazing new tools for targeting the striatum across species, from mouse to primate from my colleagues in Brain Science at the @alleninstitute.bsky.social .

www.biorxiv.org/content/10.1...

As part of our Human Immune Health Atlas release from the Allen Institute for Immunology, we built a UMAP viewer for interactive data exploration that can handle millions of cells.

You can find our Human Immune Health Atlas UMAP Explorer here:
apps.allenimmunology.org/aifi/resourc...

The Data-Driven Discovery: AI and Modeling in Biology Workshop is happening now at the Allen Institute.

I saw some great talks yesterday!

More info below, with links to recordings and the live stream, can be found here:

#openscience #machinelearning #modeling

To understand disease, we must understand the healthy immune system, deeply and across the human lifespan.

Thanks to the dedication of ~100 healthy volunteers and many research teams, we are proud to share the Human Immune Health Atlas. 🧵

#OpenScienceWeek