Loes Olde Loohuis
@loldeloo.bsky.social
Assistant professor of Psychiatry, Human Genetics, and Computational Medicine at UCLA
Reposted by Loes Olde Loohuis
Very excited to have this out! Here, we take inspiration from model selection MR to decouple direct and indirect effects in DMS experiments. Check out Jingyou's explainer and paper below:
bsky.app/profile/jing...
bsky.app/profile/jing...
How do we decouple the effects of two functional phenotypes in protein deep mutational scanning (DMS)?
Meet Cosmos, our new statistical framework for causal inference in multi-phenotype DMS.
www.biorxiv.org/content/10.1...
[1/n]
Meet Cosmos, our new statistical framework for causal inference in multi-phenotype DMS.
www.biorxiv.org/content/10.1...
[1/n]
Cosmos: A Position-Resolution Causal Model for Direct and Indirect Effects in Protein Functions
Multi-phenotype deep mutational scanning (DMS) experiments provide a powerful means to dissect how protein variants affect different layers of molecular function, such as abundance, surface expression...
www.biorxiv.org
August 15, 2025 at 4:22 PM
Very excited to have this out! Here, we take inspiration from model selection MR to decouple direct and indirect effects in DMS experiments. Check out Jingyou's explainer and paper below:
bsky.app/profile/jing...
bsky.app/profile/jing...
Applications are now open for our center’s training program! I was once a trainee in this program, and cannot recommend it highly enough
And if you consider applying, Bruna is a fantastic scientist, mentor and person!
And if you consider applying, Bruna is a fantastic scientist, mentor and person!
🚨 Applications are open for the UCLA Postdoct Training Program in Neurobehavioral Genetics 🧠🧬
Deadline: 6/30
👉 neurogen.semel.ucla.edu/curriculum/
Contact me if you're interested to write a proposal together combining genetics + functional genomics + digital phenotypes from wearables/smartphones!
Deadline: 6/30
👉 neurogen.semel.ucla.edu/curriculum/
Contact me if you're interested to write a proposal together combining genetics + functional genomics + digital phenotypes from wearables/smartphones!
Curriculum – UCLA Center for Neurobehavioral GeneticsAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontReset
neurogen.semel.ucla.edu
June 10, 2025 at 9:41 PM
Applications are now open for our center’s training program! I was once a trainee in this program, and cannot recommend it highly enough
And if you consider applying, Bruna is a fantastic scientist, mentor and person!
And if you consider applying, Bruna is a fantastic scientist, mentor and person!
Reposted by Loes Olde Loohuis
*deep breath*
Okay, I remember all the GRE discussions on Twitter. Our program is considering adding back our GRE requirement. Has anyone who removed it and considered adding back (or actually added back) the GRE requirement in computational/quantitative programs?
TIA
Okay, I remember all the GRE discussions on Twitter. Our program is considering adding back our GRE requirement. Has anyone who removed it and considered adding back (or actually added back) the GRE requirement in computational/quantitative programs?
TIA
April 25, 2025 at 9:52 PM
*deep breath*
Okay, I remember all the GRE discussions on Twitter. Our program is considering adding back our GRE requirement. Has anyone who removed it and considered adding back (or actually added back) the GRE requirement in computational/quantitative programs?
TIA
Okay, I remember all the GRE discussions on Twitter. Our program is considering adding back our GRE requirement. Has anyone who removed it and considered adding back (or actually added back) the GRE requirement in computational/quantitative programs?
TIA
I thought I could do without x but I miss my friends and I miss talking science with you all, especially now 👋🏻🦋
April 9, 2025 at 12:21 AM
I thought I could do without x but I miss my friends and I miss talking science with you all, especially now 👋🏻🦋