@lmielemdphd
lmielemdphd.bsky.social
@lmielemdphd
@lmielemdphd.bsky.social
Genetics, precision medicine, immunology, cancer research, biomedical informatics.
Happy to be part of this team! #Defendcancerresearch
Close to 200 members of AACI and the @theaacr.bsky.social + patient advocates from all walks of life registered for the 2025 AACI/AACR Hill Day, more than doubling previous records. #AACIOnTheHill #AACROnTheHill #FundNIH #FundNCI #DefendingCancerResearch #UnitedByCancerResearch #NCRM25
June 1, 2025 at 11:13 PM
Reposted by @lmielemdphd
Close to 200 members of AACI and the @theaacr.bsky.social + patient advocates from all walks of life registered for the 2025 AACI/AACR Hill Day, more than doubling previous records. #AACIOnTheHill #AACROnTheHill #FundNIH #FundNCI #DefendingCancerResearch #UnitedByCancerResearch #NCRM25
May 22, 2025 at 1:44 PM
🧪 CDC: The H5N1 virus isolated from the severe case in Louisiana contained mutations that facilitate binding to alpha2-6 sialic acid, the human receptor. These mutations were not in the birds on the patient's property and likely originated from intra-patient evolution.
www.cdc.gov/bird-flu/spo...
Genetic Sequences of Highly Pathogenic Avian Influenza A(H5N1) Viruses Identified in a Person in Louisiana
CDC has sequenced the influenza viruses in specimens collected from the patient in Louisiana who was
www.cdc.gov
December 28, 2024 at 1:21 PM
Reposted by @lmielemdphd
Climate change is driving global extinction risks, with 1.6% of species threatened at 1.3°C of warming and risks escalating to 29.7% at 5.4°C, according to a new meta-analysis in Science encompassing more than 30 years of research.

Read more:
Climate change extinctions
Climate change is expected to cause irreversible changes to biodiversity, but predicting those risks remains uncertain. I synthesized 485 studies and more than 5 million projections to produce a quantitative global assessment of climate change ...
scim.ag
December 24, 2024 at 7:56 PM
Reposted by @lmielemdphd
“The continued health of all life on the planet, including human life, depends on making choices that will protect biodiversity.”

Learn about the importance of #biodiversity and what we can do to address #BiodiversityLoss caused by human activities: https://buff.ly/4fxWVAY
December 24, 2024 at 8:34 PM
🧪 Fascinating paper on the possible early evolution of present-day genetic code.
www.pnas.org/doi/10.1073/...
Order of amino acid recruitment into the genetic code resolved by last universal common ancestor’s protein domains | PNAS
The current “consensus” order in which amino acids were added to the genetic code is based on potentially biased criteria, such as the absence of s...
www.pnas.org
December 23, 2024 at 5:51 PM
Reposted by @lmielemdphd
🧠 We have measured the speed of thought

Researchers measured human thought at 10 bits/s – far slower than our sensory systems, which gather 1 billion bits/s, equivalent to streaming 125 MB of data per second.

🔗 www.cell.com/neuron/abstr...

#Neuroscience #Brain #Cognition #SciComm 🧪
The unbearable slowness of being: Why do we live at 10 bits/s?
Zheng and Meister write about the paradoxical slowness of human behavior. Although our senses gather data at 109 bits/s, our overall information throughput is only 10 bits/s. This stark contrast touches on many fundamental aspects of brain function.
www.cell.com
December 22, 2024 at 12:24 PM
Reposted by @lmielemdphd
🧠🤖 Chatbots show cognitive decline

This @bmj.com study finds that leading large language models show signs of mild cognitive impairment in tests used to detect early dementia.

The older the model, the lower the score

🔗 press.psprings.co.uk/bmj/december...

#AI #Neurology 🧪 #SciComm
press.psprings.co.uk
December 19, 2024 at 9:19 PM
This is why regulations and regulatory agencies are necessary.

www.newsweek.com/supplement-r...
Supplement recall over "serious or even fatal" poisoning danger
A list of supplements has been recalled after a poisonous plant called yellow oleander was discovered in some samples.
www.newsweek.com
December 16, 2024 at 6:01 PM
🧪Hopefully this is a false alarm, but there is reason for concern.
www.nbcnews.com/health/healt...
Patient hospitalized with possible bird flu infection in Louisiana
The individual had been exposed to sick or dead birds thought to have had the virus, health officials said.
www.nbcnews.com
December 14, 2024 at 9:40 PM
Reposted by @lmielemdphd
🧪
Here's what we know about "Disease X," the mysterious disease that has sickened several hundred people and killed at least 31 children in the DRC. Many samples tested positive for malaria, but there could be multiple diseases. By @pauladepoju.bsky.social www.scientificamerican.com/article/myst...
Why the Mysterious 'Disease X' Outbreak Is So Hard to Investigate
Authorities in the Democratic Republic of the Congo are racing to identify a deadly illness that is affecting malnourished children
www.scientificamerican.com
December 12, 2024 at 1:28 AM
Genetically engineered, harmless bacteria as cancer immunotherapy. Potentially transformative studies.

www.cancer.gov/news-events/...
Engineered E. coli Shrink Tumors in Mice
The probiotic bacterium E. coli Nissle 1917 can be genetically engineered to help the immune system attack tumors, two new studies show.
www.cancer.gov
December 11, 2024 at 11:12 PM
Scientific illiteracy and science denial are a fertile environment for disinformation. Accurate descriptions of how science works are the antidote. The BBC has 2 great science podcasts that cover issues from medicine to physics in a clear, entertaining format: Science in Action and Inside Science.
Such a good capture of all the versions of science denial in the world. I see a lot of it in climate and a little in weather, and you see the same issues in other "controversial" sciences (vaccines, GMOs, evolution, stem cell research, reproductive health care, etc.).
This is so spot on. As a climate scientist and public intellectual, I see or experience these often
December 10, 2024 at 3:49 PM
Reposted by @lmielemdphd
The Leadership Consortium: Collaboration for a Learning Health System provides a trusted venue for national leaders to work cooperatively toward achieving effective, efficient, equitable health care that is continuously learning at every level. Learn more: nam.edu/NAMLeadershipConsortium
Value and Science-Driven Health Care - National Academy of Medicine
The NAM’s Leadership Consortium: Collaboration for a Learning Health System provides a trusted venue for national leaders in health and health care to work cooperatively toward their common…
nam.edu
December 9, 2024 at 3:43 PM
Reposted by @lmielemdphd
Infection with SARS-CoV-2 has highlighted how altered endothelial functions contribute to multiorgan health effects during the acute phase of COVID-19 and potentially to the longer-term consequences associated with #LongCovid.

Learn more in a new #SciencePerspective: scim.ag/3OOaaCM
Endothelial inflammation in COVID-19
Disrupted endothelial function underlies the multiorgan complications of COVID-19
scim.ag
December 9, 2024 at 9:03 PM
Reposted by @lmielemdphd
For the second time in 2 years, #mpox poses a global threat. Can the long-overlooked virus be contained? scim.ag/3VwwvIW
Can Congo contain its exploding mpox epidemic—and curtail its international spread?
Efforts to control the virus are hampered by vaccine shortages, logistical problems, and bureaucracy
scim.ag
December 10, 2024 at 2:30 PM