Sam
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llssam.bsky.social
Sam
@llssam.bsky.social
27 followers 98 following 0 posts
Lattice lightsheet enthusiast, lager-enjoyer
Postdoc in Culley Group at King’s College London
she/her
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Reposted by Sam
superresolusian.bsky.social
Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5)
www.biorxiv.org/content/10.1...
Image quality metrics fail to accurately represent biological information in fluorescence microscopy
Image processing methods offer the potential to improve the quality of fluorescence microscopy data, allowing for image acquisition at lower, less phototoxic illumination doses. The training and evalu...
www.biorxiv.org
August 7, 2025 at 1:00 PM
Reposted by Sam
jcellsci.bsky.social
In their Opinion article, Samantha Webster @llssam.bsky.social, Remi Brynn and Kate Poole @katepoole.bsky.social consider how perspectives from both cell biologists and biophysicists will be crucial for characterising mechanosensitive ion channels in vivo.
journals.biologists.com/jcs/article/...
Examples of in vitro measurements (left panel) and the in vivo mechanical landscapes where tissues and cells experience complex compound forces (right panel). In vitro experimental techniques can provide detailed information about specific properties of mechanosensitive ion channels. However, an experimental gap remains in understanding how channels are activated and the consequences of their function in complex in vivo settings.
August 7, 2025 at 9:23 AM