Liz Gallagher
lizgallagher900.bsky.social
Liz Gallagher
@lizgallagher900.bsky.social
Post-doc | Salk Institute
PhD | UPenn
Reposted by Liz Gallagher
Arp2/3 nucleates bidirectional linear actin filaments when activated by SPIN90 !!! www.biorxiv.org/content/10.1...
Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers in metazoans
Branched actin networks nucleated by the Arp2/3 complex play critical roles in various cellular processes, from cell migration to intracellular transport. However, when activated by WISH/DIP/SPIN90 fa...
www.biorxiv.org
January 31, 2025 at 2:31 PM
Reposted by Liz Gallagher
So proud of Adam Fenton and his work defining the role of FMRP in the local regulation of mitochondrial fission in neurons via local translation: www.nature.com/articles/s41...
FMRP regulates MFF translation to locally direct mitochondrial fission in neurons - Nature Cell Biology
Fenton et al. show that FMRP granules dock at the mitochondrial midzone in a Rab7-dependent manner in axons and dendrites, where they promote local MFF synthesis and fission at the mitochondrial midzo...
www.nature.com
November 15, 2024 at 4:57 PM