linhngk.bsky.social
@linhngk.bsky.social
Reposted
Excited to share a new method developed from my group thats published at Genome Biology. This was an amazing effort by my grad student Linh @linhngk.bsky.social. We developed Topsicle, a method that analyzes long read data for telomere analysis and length measuring.
doi.org/10.1186/s130...
Topsicle: a method for estimating telomere length from whole genome long-read sequencing data - Genome Biology
Telomeres protect chromosome ends and their length varies significantly between organisms. Because telomere length variation is associated with various biomedical and eco-evolutionary phenotypes, many...
doi.org
September 22, 2025 at 2:18 PM
Reposted
I'm very excited to share a new method my grad student @linhngk.bsky.social and I have developed. Here's Topsicle a new computational method for analyzing long read sequencing data and estimate telomere length. Please see our preprint or this thread for detail!
www.biorxiv.org/content/10.1...
Topsicle: a method for estimating telomere length from whole genome long-read sequencing data
Telomeres protect chromosome ends and its length varies significantly between organisms. Because telomere length variation is associated with various biomedical and eco-evolutionary phenotypes, many b...
www.biorxiv.org
July 15, 2025 at 2:14 PM