Genetic & cancer epidemiology
Views my own 🇺🇦🇽🇰🇨🇦
investigations.hopenothate.org.uk/superbaby-fa...
investigations.hopenothate.org.uk/superbaby-fa...
Genetic correlation is straightforward but remember HLA - largely impacting T1D & other AIDs - is excluded by LDSC.
If genetic correlation is a genome-wide non-HLA measurement, how can we get HLA back into the game?
We built a within-sample HLA PGS with weighted ridge classifiers in FinnGen.
Genetic correlation is straightforward but remember HLA - largely impacting T1D & other AIDs - is excluded by LDSC.
If genetic correlation is a genome-wide non-HLA measurement, how can we get HLA back into the game?
We built a within-sample HLA PGS with weighted ridge classifiers in FinnGen.