See you all next year for the 25th #GeneForum and some Estonian music! #plusskoor

And so many other excellent speakers like @srubinacci.bsky.social @stevesphd.bsky.social @hilarycmartin.bsky.social & many more who made it an awesome conference - now called mini-ASHG (by Hilary Martin) and we loved it 🥰

2nd day opened with a BEAUTIFUL talk by @nickywhiffin.bsky.social about ReNu variants playing such a huge role in developmental disorders despite the few bases..!

So excited about this year’s Gene Forum in Tartu being kicked off now by our keynote speaker @eimearekenny.bsky.social 🤩

Key findings:
🔹Polygenic liability to complex traits and PGx variation contribute to dose variability.
🔹PGS for BMI and the indicator trait associated with statins, metoprolol, and warfarin.
🔹GWAS confirmed known signals for metoprolol (CYP2D6), and warfarin (VKORC1, CYP2C9).

We applied different strategies to derive dose metrics for cardiovascular and psychiatric medications (statins, metoprolol, warfarin, antidepressants and antipsychotics):
🔹 Daily dose per purchase
🔹 Median dose across purchases
🔹 Maximum purchased dose

This is what happens when you return research results to biobank participants:
✅ The 2nd most googled “How to…?” question in Estonia 2024: “How to become a biobank participant?”
✅ "Estonian Biobank" among Top 10 search terms.
Huge thanks to the entire UniTartu & EstBB teams! ✨