Luis Ferrández Peral
@lferrandez.bsky.social
Postdoctoral Researcher at Scheiffele Lab
Biozentrum University of Basel 🇨🇭
RNA, evolution and neurobiology
Biozentrum University of Basel 🇨🇭
RNA, evolution and neurobiology
Reposted by Luis Ferrández Peral
🌍Marta Melé: “Con lo que hemos descubierto, hemos construido un mapa génico no sesgado que nos ha confirmado que toda la comunidad científica está perdiendo la oportunidad de estudiar variantes genéticas de ascendencias no europeas"”.
➡ www.bsc.es/4oc
➡ www.bsc.es/4oc
www.bsc.es
December 3, 2025 at 10:03 AM
🌍Marta Melé: “Con lo que hemos descubierto, hemos construido un mapa génico no sesgado que nos ha confirmado que toda la comunidad científica está perdiendo la oportunidad de estudiar variantes genéticas de ascendencias no europeas"”.
➡ www.bsc.es/4oc
➡ www.bsc.es/4oc
Reposted by Luis Ferrández Peral
How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Conservation of regulatory elements with highly diverged sequences across large evolutionary distances
Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...
rdcu.be
May 27, 2025 at 12:19 PM
How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Reposted by Luis Ferrández Peral
🚨New preprint from @bonevlab.bsky.social 🚨: What are the key epigenetic mechanisms that drive species-specific gene regulation during primate neurogenesis - and how do they contribute to the evolution of the human neocortex?
Here’s what we discovered 👇
www.biorxiv.org/content/10.1...
Here’s what we discovered 👇
www.biorxiv.org/content/10.1...
3D Epigenome Evolution Underlies Divergent Gene Regulatory Programs in Primate Neural Development
The expansion of the neocortex is a hallmark of human evolution and is closely linked to neural stem cell biology. Yet, the epigenetic mechanisms driving divergent gene regulation during primate neuro...
www.biorxiv.org
March 13, 2025 at 9:59 AM
🚨New preprint from @bonevlab.bsky.social 🚨: What are the key epigenetic mechanisms that drive species-specific gene regulation during primate neurogenesis - and how do they contribute to the evolution of the human neocortex?
Here’s what we discovered 👇
www.biorxiv.org/content/10.1...
Here’s what we discovered 👇
www.biorxiv.org/content/10.1...
Reposted by Luis Ferrández Peral
Proud to see this manuscript by @carolinamonzo.bsky.social from @conesalab.bsky.social in collaboration with #SoniaTarazona´s team. MOSIM simulates any type of (multi)epigenomics data that may regulate gene expression. academic.oup.com/bib/article/... @hitseq.bsky.social @iscb-regsys.bsky.social
MOSim: bulk and single-cell multilayer regulatory network simulator
Abstract. As multi-omics sequencing technologies advance, the need for simulation tools capable of generating realistic and diverse (bulk and single-cell)
academic.oup.com
March 22, 2025 at 4:01 PM
Proud to see this manuscript by @carolinamonzo.bsky.social from @conesalab.bsky.social in collaboration with #SoniaTarazona´s team. MOSIM simulates any type of (multi)epigenomics data that may regulate gene expression. academic.oup.com/bib/article/... @hitseq.bsky.social @iscb-regsys.bsky.social
Reposted by Luis Ferrández Peral
Thrilled to see our Perspective on long-read transcriptomics Published in Advance in @genomeresearch.bsky.social, with #AdamFrankish and @carolinamonzo.bsky.social. We discuss the opportunities and challenges of LRS to uncover Transcript Divergence and for Genome Annotation. tinyurl.com/bdeteu4j
March 4, 2025 at 6:56 AM
Thrilled to see our Perspective on long-read transcriptomics Published in Advance in @genomeresearch.bsky.social, with #AdamFrankish and @carolinamonzo.bsky.social. We discuss the opportunities and challenges of LRS to uncover Transcript Divergence and for Genome Annotation. tinyurl.com/bdeteu4j