There are many ways to make your voice heard and participate in all that the #ISSCR2026 Annual Meeting has to offer! Discover how to get involved, including submitting an abstract, proposing a science spotlight, hosting a meet-up hub, and more! invt.io/1lxby1coomp @isscr.org

5/5 Together, our study introduces a powerful tool for investigating stem cell potency and offers key insights into the regulation of early embryonic development.

4/5 We also leveraged this reporter system to study regulators of cellular potency.

2/5 Unexpectedly, we found that the simultaneous expression of LTR5_Hs and MER51B marks rare, metastable primed cells. These cells are associated with DNA damage and express preimplantation-stage transcripts.

1/5 We have developed a novel dual-fluorescence reporter system that allows us to track cells during transitions between pluripotent states and stem cell differentiation at single-cell resolution.