Unfortunately, there is no simple answer and as always, the method depends on the research question. However, these four methods have now all been included into Lead-DBS/OSS-DBS and can be conveniently analyzed on group level using the FiberFiltering Explorer (www.lead-dbs.org).

Should we use
• Electric Field Magnitude
• Electric Field projections onto fibers
• Pathway Activation Modeling
• probabilistic Pathway Activation Modeling?

How should we best model recruitment of axons by deep brain stimulation?
Various concepts have been introduced and Konstantin Butenko just introduced a few more in a new publication at Brain Communications:

academic.oup.com/braincomms/a...

Lighting effects.. 🎉💥

Lead-DBS v3.2 is out now – featuring Lead-Tutor, lots of code fixes and improvements, as well as some new atlases. Read all about it here:

www.lead-dbs.org?na=view&id=31

First paper to ever use a 12-year-old feature of Lead-DBS which is to visualize graph networks, implemented still during the PhD of @andreashorn.org and pretty obscure in a tool called lead groupconnectome.

Achtzehn et al. on STN-DBS ➔ Cognitive Control:

onlinelibrary.wiley.com/doi/10.1002/...

The Courtin lab is always pretty neat with illustrations and their grey & red signature figures. What would they do with electrode localizations done with Lead-DBS? See @natureportfolio.bsky.social Nature Medicine paper on hypothalamic DBS for spinal cord injury here:

www.nature.com/articles/s41...

New, good things are coming!

Lead-DBS is on @bsky.app! 👋