Laszlo Dobson
@ldobson.bsky.social
Postdoc at RCNS (Tusnady lab), ex-EMBL (Gibson Team). Membrane proteins, linear motifs, pathogens.
Our paper about #Leishmania linear motifs is out! We describe three protein sorting systems critical for Leishmania, that are greatly diverged from their host counterparts: secretory signal peptides, ER retention motifs, and autophagy signals.
doi.org/10.1371/jour...
doi.org/10.1371/jour...
Linear motifs regulating protein secretion, sorting and autophagy in Leishmania parasites are diverged with respect to their host equivalents
Author summary Leishmaniasis is a detrimental disease which causes significant decrease in quality of life and in severe cases can be lethal. The disease is caused by the pathogen Leishmania spread by...
doi.org
February 17, 2024 at 6:14 AM
Our paper about #Leishmania linear motifs is out! We describe three protein sorting systems critical for Leishmania, that are greatly diverged from their host counterparts: secretory signal peptides, ER retention motifs, and autophagy signals.
doi.org/10.1371/jour...
doi.org/10.1371/jour...
Reposted by Laszlo Dobson
Deep learning driven de novo drug design based on gastric proton pump structures Communications Biology 6, 956 www.nature.com/articles/s42... Now in PDBTM: pdbtm.unitmp.org/entry/8ijv
January 8, 2024 at 1:05 PM
Deep learning driven de novo drug design based on gastric proton pump structures Communications Biology 6, 956 www.nature.com/articles/s42... Now in PDBTM: pdbtm.unitmp.org/entry/8ijv