Laura Schaedel
lauraschaedel.bsky.social
Laura Schaedel
@lauraschaedel.bsky.social
Microtubule & intermediate filament aficionada
Reposted by Laura Schaedel
🚨Great News!🚨
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.

Congrats @marianattom.bsky.social

www.biorxiv.org/content/10.1...
September 16, 2025 at 11:39 AM
Reposted by Laura Schaedel
🎉New Paper Drop🎉 We just uploaded our latest findings on bioRxiv!

We report the identification of the limits of microtubule self-repair and how microtubule integrity is maintained under mechanical load.

Congratulations @bucklingmt.bsky.social

www.biorxiv.org/content/10.1...
September 14, 2025 at 8:11 AM
Reposted by Laura Schaedel
Have you ever wondered how microtubules withstand and respond to mechanical stress in cells?

Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.
September 16, 2025 at 6:43 AM
Reposted by Laura Schaedel
Are you ready for a symposium dedicated to microtubule dynamics, function, and structure? 🙌

#EESMicrotubules will bring together researchers who share an interest in microtubule biology and its relevance to health and disease 🩺

💻 s.embl.org/ees26-09-bl
✒️ Submit your abstract by 11 March
September 11, 2025 at 2:13 PM
Reposted by Laura Schaedel
A big thank you to my amazing PI Laura Schaedel, my colleagues @schaedellab.bsky.social , Mirko Wieczorek, Constantin Albrecht, @stefandiezlab.bsky.social , @manuelthery.bsky.social and the team of Ludger Santen😀🧵 (9/9).
September 14, 2025 at 10:15 AM