Louise Huuki-Myers
lahuuki.bsky.social
Louise Huuki-Myers
@lahuuki.bsky.social
Staff Scientist at LIBD studying brain transcriptomics with #RStats 🧠
PhD Student in Neuroscience at University of Cambridge
lahuuki.github.io
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
doi.org
November 4, 2025 at 9:31 PM
Learning more about APOE differences in the cell types of the brain 🧠

I presented "APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease" from @zhaonaa.bsky.social at our team journal club, check it out!

doi.org/10.1016/j.ne...

▶️ youtu.be/L4J9jFS-Pic
Redirecting
doi.org
May 28, 2025 at 6:33 PM
Reposted by Louise Huuki-Myers
Hi! Check my journal club talk: smart ML method to deconvolute pooled snRNA-seq using sex-specific expression🧬

Thanks @daylab.bsky.social & @rphillips3.bsky.social for this approach🙌

🎥 youtu.be/zpeCFwYfV3o
🛝 speakerdeck.com/manishabarse

#snRNAseq #ML #Bioinformatics @lieberinstitute.bsky.social
[2025-04-23] Journal club on "[...] deconvolution of pooled snRNA-seq using sex-dependent gene expr"
YouTube video by Leonardo Collado Torres
youtu.be
May 22, 2025 at 9:51 PM
April 25, 2025 at 3:25 PM
Hey #deconvolution fans! 👀 We’ve got an exciting new publication for you: a benchmark of 6 popular deconvolution methods on a multimodal human brain #DLPFC dataset 🧠🧬
Now out in Genome Biology: doi.org/10.1186/s130...

@lieberinstitute.bsky.social @jhubiostat.bsky.social
Benchmark of cellular deconvolution methods using a multi-assay dataset from postmortem human prefrontal cortex - Genome Biology
Cellular deconvolution of bulk RNA-sequencing data using single cell/nuclei RNA-seq reference data is an important strategy for estimating cell type composition in heterogeneous tissues, such as the h...
doi.org
April 11, 2025 at 2:35 PM
Check out my journal club presentation on the crumblr pre-print from Hoffman and Roussos, a new method to analyze differential composition in #singlecell data 🍪
Looks very useful for single cell RNA-seq data with case/control study design 🤔
📄 doi.org/10.1101/2025...
▶️ www.youtube.com/watch?v=Hi5E...
Fast, flexible analysis of differences in cellular composition with crumblr
Changes in cell type composition play an important role in human health and disease. Recent advances in single-cell technology have enabled the measurement of cell type composition at increasing cell ...
doi.org
February 14, 2025 at 10:23 AM
Reposted by Louise Huuki-Myers
Check our recent video "[2025-01-29] R/Bioconductor-powered Team Data Science: TLDR version 2025"
youtu.be/alL-g2roXxM

We go over what analyses our @lieberinstitute.bsky.social has expertise on 💻

Slides orchestrated by @lahuuki.bsky.social at speakerdeck.com/lahuuki/2025...

👥 go.bsky.app/53gy4UP
February 12, 2025 at 9:35 PM
Reading the instructions first next time 😅

completed "Ceres Search" - Day 4 - Advent of Code 2024 #AdventOfCode adventofcode.com/2024/day/4
Day 4 - Advent of Code 2024
adventofcode.com
December 4, 2024 at 10:22 PM
I've completed "Red-Nosed Reports" - Day 2 - Advent of Code 2024 🔴 #AdventOfCode adventofcode.com/2024/day/2
Day 2 - Advent of Code 2024
adventofcode.com
December 2, 2024 at 11:25 PM
Reposted by Louise Huuki-Myers
I decided to make a starter pack for members/alumni of @lieberinstitute.bsky.social "Data Science Team 1" 💻

Initially led by @aejaffe.bsky.social until 2020/09; then by me. In 2024, the team became part of the Division of Translational Neuroscience led by @martinowk.bsky.social

go.bsky.app/53gy4UP
November 12, 2024 at 4:25 PM
Hi Bluesky! 👋 I'm Louise Huuki-Myers I work on transciptomic research in the brain 🧠🧬 @lieberinstitute.bsky.social and am Studying for my PhD in #neuroscience at the University of Cambridge. Excited to share more about neurosci research and #Rstats here 🦋
November 12, 2024 at 12:22 PM