Waggoner Lab
@labwaggoner.bsky.social
Focused on innate immune mechanisms governing pathogenesis of disease and on NK-cell based therapies for disease. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
Limited vaccine-induced CD8+ T cell immunity in HIV-infected immunological nonresponders @insight.jci.org
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
November 11, 2025 at 5:07 PM
Limited vaccine-induced CD8+ T cell immunity in HIV-infected immunological nonresponders @insight.jci.org
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
Comparative analysis of adenovirus, mRNA, and protein vaccines reveals context-dependent immunogenicity and efficacy @insight.jci.org @harvardmed.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
November 11, 2025 at 5:05 PM
Comparative analysis of adenovirus, mRNA, and protein vaccines reveals context-dependent immunogenicity and efficacy @insight.jci.org @harvardmed.bsky.social
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
@biorxivpreprint.bsky.social Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-kB
www.biorxiv.org/content/10.1... @genecenter-lmu.bsky.social
www.biorxiv.org/content/10.1... @genecenter-lmu.bsky.social
November 11, 2025 at 1:38 PM
@biorxivpreprint.bsky.social Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-kB
www.biorxiv.org/content/10.1... @genecenter-lmu.bsky.social
www.biorxiv.org/content/10.1... @genecenter-lmu.bsky.social
Impact of disease-associated chromatin accessibility QTLs across immune cell types and contexts
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
November 11, 2025 at 1:35 PM
Impact of disease-associated chromatin accessibility QTLs across immune cell types and contexts
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Myosin-II-dependent actomyosin contractility is a critical mechanical structure regulating single-cell thermo-adaptability, with physiological implications for tuning the speed of immune responses in vivo @cp-devcell.bsky.social
www.cell.com/developmenta...
www.cell.com/developmenta...
November 11, 2025 at 1:22 PM
Myosin-II-dependent actomyosin contractility is a critical mechanical structure regulating single-cell thermo-adaptability, with physiological implications for tuning the speed of immune responses in vivo @cp-devcell.bsky.social
www.cell.com/developmenta...
www.cell.com/developmenta...
OAS1 and OAS3 genetic variants enhance inflammatory responses to SARS-CoV-2 @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
November 11, 2025 at 1:20 PM
OAS1 and OAS3 genetic variants enhance inflammatory responses to SARS-CoV-2 @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
CD2 costimulation strength: A key regulator of T cell function and anti-tumor immunity that is epigenetically regulated @cp-iscience.bsky.social www.cell.com/iscience/ful...
November 11, 2025 at 1:18 PM
CD2 costimulation strength: A key regulator of T cell function and anti-tumor immunity that is epigenetically regulated @cp-iscience.bsky.social www.cell.com/iscience/ful...
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
November 10, 2025 at 5:59 PM
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
Inhibition of a cancer-specific transcript LISRR makes human drug-tolerant persister cells visible to the immune system and re-sensitizes cancer cells to immune checkpoint blockade @jem.org @leuccilrcb.bsky.social
rupress.org/jem/article/...
rupress.org/jem/article/...
November 10, 2025 at 5:58 PM
Inhibition of a cancer-specific transcript LISRR makes human drug-tolerant persister cells visible to the immune system and re-sensitizes cancer cells to immune checkpoint blockade @jem.org @leuccilrcb.bsky.social
rupress.org/jem/article/...
rupress.org/jem/article/...
THDF2 in dendritic cells negatively regulates antitumor immunity of radiotherapy @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
November 10, 2025 at 5:53 PM
THDF2 in dendritic cells negatively regulates antitumor immunity of radiotherapy @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
Distinct autoreactive CD19– plasma cell subsets accumulate in lupus-prone mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 10, 2025 at 5:50 PM
Distinct autoreactive CD19– plasma cell subsets accumulate in lupus-prone mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Respiratory immunization using antibiotic-inactivated Bordetella pertussis confers T cell-mediated protection against nasal infection in mice
www.nature.com/articles/s41...
@natmicrobiol.nature.com @tcddublin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@natmicrobiol.nature.com @tcddublin.bsky.social
www.nature.com/articles/s41...
November 10, 2025 at 5:47 PM
Respiratory immunization using antibiotic-inactivated Bordetella pertussis confers T cell-mediated protection against nasal infection in mice
www.nature.com/articles/s41...
@natmicrobiol.nature.com @tcddublin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@natmicrobiol.nature.com @tcddublin.bsky.social
www.nature.com/articles/s41...
Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
November 10, 2025 at 5:45 PM
Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
CLEC12A signaling represses protective immune responses and contributes to hippocampal pathology in neurotropic picornavirus infection
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 10, 2025 at 5:43 PM
CLEC12A signaling represses protective immune responses and contributes to hippocampal pathology in neurotropic picornavirus infection
www.nature.com/articles/s41...
www.nature.com/articles/s41...
131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 10, 2025 at 5:43 PM
131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Perspective @naturemedicine.bsky.social @jjaimemiranda.bsky.social
Maximizing researcher–policymaker engagement in global public health
www.nature.com/articles/s41...
Maximizing researcher–policymaker engagement in global public health
www.nature.com/articles/s41...
November 10, 2025 at 5:38 PM
Perspective @naturemedicine.bsky.social @jjaimemiranda.bsky.social
Maximizing researcher–policymaker engagement in global public health
www.nature.com/articles/s41...
Maximizing researcher–policymaker engagement in global public health
www.nature.com/articles/s41...
Firewater, fructose and appetite @natmetabolism.nature.com
www.nature.com/articles/s42... @cudenver.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42... @cudenver.bsky.social
www.nature.com/articles/s42...
November 10, 2025 at 5:31 PM
Firewater, fructose and appetite @natmetabolism.nature.com
www.nature.com/articles/s42... @cudenver.bsky.social
www.nature.com/articles/s42...
www.nature.com/articles/s42... @cudenver.bsky.social
www.nature.com/articles/s42...
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models airan-lab.stanford.edu @stanforduniversity.bsky.social
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41...
November 10, 2025 at 5:27 PM
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models airan-lab.stanford.edu @stanforduniversity.bsky.social
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41... @natbiotech.nature.com
www.nature.com/articles/s41...
Nirmatrelvir-ritonavir should be prescribed immediately after COVID-19 diagnosis for achieving its greatest benefit on improving post-COVID outcomes
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
November 10, 2025 at 5:25 PM
Nirmatrelvir-ritonavir should be prescribed immediately after COVID-19 diagnosis for achieving its greatest benefit on improving post-COVID outcomes
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
Chromatin remodeling enhances MAP3K8 expression in HTLV-1-associated myelopathy: a key pathogenesis for therapeutic intervention @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 10, 2025 at 5:23 PM
Chromatin remodeling enhances MAP3K8 expression in HTLV-1-associated myelopathy: a key pathogenesis for therapeutic intervention @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Gut intraepithelial lymphocytes interact with neutrophils during sepsis and facilitate NETosis, which activates Kupffer cells to contribute to sepsis-induced liver injury @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 10, 2025 at 5:21 PM
Gut intraepithelial lymphocytes interact with neutrophils during sepsis and facilitate NETosis, which activates Kupffer cells to contribute to sepsis-induced liver injury @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Review: Auto-Abs against type I IFNs: Strong, common, and global determinants of severe arboviral diseases @jhumimmunity.org @casanovalab.bsky.social @shenyingzhang1.bsky.social rupress.org/jhi/article/...
November 10, 2025 at 5:03 PM
Review: Auto-Abs against type I IFNs: Strong, common, and global determinants of severe arboviral diseases @jhumimmunity.org @casanovalab.bsky.social @shenyingzhang1.bsky.social rupress.org/jhi/article/...
A systematic literature review of CVID reveals pervasive detrimental noninfectious manifestations @jhumimmunity.org
rupress.org/jhi/article/...
rupress.org/jhi/article/...
November 10, 2025 at 5:01 PM
A systematic literature review of CVID reveals pervasive detrimental noninfectious manifestations @jhumimmunity.org
rupress.org/jhi/article/...
rupress.org/jhi/article/...
Review @jhumimmunity.org @casanovalab.bsky.social
The seven enigmas of SARS-CoV-2: From the past to the future
rupress.org/jhi/article/...
The seven enigmas of SARS-CoV-2: From the past to the future
rupress.org/jhi/article/...
November 10, 2025 at 4:59 PM
Review @jhumimmunity.org @casanovalab.bsky.social
The seven enigmas of SARS-CoV-2: From the past to the future
rupress.org/jhi/article/...
The seven enigmas of SARS-CoV-2: From the past to the future
rupress.org/jhi/article/...
Review: Pathogenic drivers of lupus myocarditis and potential therapeutic targets @taejoonw.bsky.social
www.nature.com/articles/s12...
www.nature.com/articles/s12...
November 9, 2025 at 10:34 PM
Review: Pathogenic drivers of lupus myocarditis and potential therapeutic targets @taejoonw.bsky.social
www.nature.com/articles/s12...
www.nature.com/articles/s12...