Kalyani Bambal
@kriyer.bsky.social
Pathologist.Interests in
#surgicalpath #breastpath #bstpath #gupath #oncopath
#surgicalpath #breastpath #bstpath #gupath #oncopath
Reposted by Kalyani Bambal
Reposted by Kalyani Bambal
This is classic morphology for a GLI1 coamplified differentiated liposarcoma with perineurial-like whorls. So now the MDM2 amplification makes sense. The current tumor is showing essentially classical features of a GLI1 amplified soft tissue sarcoma. So the morphology/molecular explain each other.
June 12, 2025 at 9:10 PM
This is classic morphology for a GLI1 coamplified differentiated liposarcoma with perineurial-like whorls. So now the MDM2 amplification makes sense. The current tumor is showing essentially classical features of a GLI1 amplified soft tissue sarcoma. So the morphology/molecular explain each other.
All that palisades etc etc.Seen an endometrial stromal sarcoma with crazy palisading just like this.
June 4, 2025 at 4:46 PM
All that palisades etc etc.Seen an endometrial stromal sarcoma with crazy palisading just like this.
Reposted by Kalyani Bambal
So- desmoid fibromatosis with bizarre cells and p53 mutant pattern- r/o Li-Fraumeni syndrome.
Happy Friday!
pubmed.ncbi.nlm.nih.gov/36908221/
Happy Friday!
pubmed.ncbi.nlm.nih.gov/36908221/
Desmoid Fibromatosis With TP53 Mutation and Striking Nuclear Pleomorphism - PubMed
Desmoid fibromatosis is a myofibroblastic neoplasm of intermediate biologic potential, which has a strong predilection for local recurrence but does not metastasize. Arranged in long, sweeping fascicl...
pubmed.ncbi.nlm.nih.gov
May 30, 2025 at 5:38 PM
So- desmoid fibromatosis with bizarre cells and p53 mutant pattern- r/o Li-Fraumeni syndrome.
Happy Friday!
pubmed.ncbi.nlm.nih.gov/36908221/
Happy Friday!
pubmed.ncbi.nlm.nih.gov/36908221/
Beautiful MIFS thanks.
May 12, 2025 at 1:58 PM
Beautiful MIFS thanks.
Reposted by Kalyani Bambal
This of course is what we now call “myxoinflammatory fibroblastic sarcoma”. Originally reported as “Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells”. I think this older name helps us remember the distinctive diagnostic features of this sarcoma.
April 29, 2025 at 6:46 PM
This of course is what we now call “myxoinflammatory fibroblastic sarcoma”. Originally reported as “Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells”. I think this older name helps us remember the distinctive diagnostic features of this sarcoma.
Reposted by Kalyani Bambal
Degenerating vegetable. Likely a ruptured diverticulitis with a big reactive soft tissue mass. Happy Friday!!
May 2, 2025 at 6:25 PM
Degenerating vegetable. Likely a ruptured diverticulitis with a big reactive soft tissue mass. Happy Friday!!
Reposted by Kalyani Bambal
Those of you following my cases know the answer is usually “look at the slides some more”.
May 2, 2025 at 6:24 PM
Those of you following my cases know the answer is usually “look at the slides some more”.