Krishna Singh Bisht
@krishnasbisht.bsky.social
PhD Candidate @UNESCO Regional Centre for Biotechnology, India. Studying neuroinflammation and protein aggregation.
Our recent journal club @jphysiol.bsky.social summarises the role of nitrate supplementation in improving age-associated neuromuscular outcomes. Congratulations to @jaydeepsharma.bsky.social , Ifrah, & Anamika. Sincere thanks to Prof.Tushar K Maiti & Prof. Sam J Mathew for their guidance.
Dietary nitrate supplementation improves age‐associated neuromuscular outcomes: A step towards healthy ageing
Click on the article title to read more.
physoc.onlinelibrary.wiley.com
June 25, 2025 at 8:18 PM
Our recent journal club @jphysiol.bsky.social summarises the role of nitrate supplementation in improving age-associated neuromuscular outcomes. Congratulations to @jaydeepsharma.bsky.social , Ifrah, & Anamika. Sincere thanks to Prof.Tushar K Maiti & Prof. Sam J Mathew for their guidance.
Reposted by Krishna Singh Bisht
A class of life-saving antibiotics called aminoglycosides can cause irreversible hearing loss by damaging inner ear hair cells. However, using CRISPR to inhibit the autophagy protein GABARAP prevented hearing loss in mice. In PNAS: www.pnas.org/doi/10.1073/...
February 18, 2025 at 7:57 PM
A class of life-saving antibiotics called aminoglycosides can cause irreversible hearing loss by damaging inner ear hair cells. However, using CRISPR to inhibit the autophagy protein GABARAP prevented hearing loss in mice. In PNAS: www.pnas.org/doi/10.1073/...
Reposted by Krishna Singh Bisht
Deletion of thrombospondin-1 prevents inflammaging and preserves blood stem cell fitness during aging
@scienceimmuno.bsky.social
www.science.org/doi/10.1126/...
@scienceimmuno.bsky.social
www.science.org/doi/10.1126/...
January 3, 2025 at 7:28 PM
Deletion of thrombospondin-1 prevents inflammaging and preserves blood stem cell fitness during aging
@scienceimmuno.bsky.social
www.science.org/doi/10.1126/...
@scienceimmuno.bsky.social
www.science.org/doi/10.1126/...
Reposted by Krishna Singh Bisht
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
December 11, 2024 at 5:04 PM
3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)
Reposted by Krishna Singh Bisht
5th person to be cured of HIV
“Today, researchers announced the Dusseldorf patient still has no detectable virus in his body, even after stopping his HIV medication four years ago.”
“Today, researchers announced the Dusseldorf patient still has no detectable virus in his body, even after stopping his HIV medication four years ago.”
5th person confirmed to be cured of HIV
Researchers are announcing that a 53-year-old man in Germany has been cured of HIV.
abcnews.go.com
December 11, 2024 at 7:19 AM
5th person to be cured of HIV
“Today, researchers announced the Dusseldorf patient still has no detectable virus in his body, even after stopping his HIV medication four years ago.”
“Today, researchers announced the Dusseldorf patient still has no detectable virus in his body, even after stopping his HIV medication four years ago.”
Reposted by Krishna Singh Bisht
Scared to share this after 10 freaking years of waiting, but here we go: We found that temperature *perception* can change the biology of the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Perception of Temperature Even in the Absence of Actual Change is Sufficient to Drive Transgenerational Epigenetic Inheritance
Can processes occurring in one individuals nervous system influence the physiology of the descendants? Here we explored the provocative hypothesis that parents sensation or perception of environmental...
www.biorxiv.org
December 5, 2024 at 7:32 PM
Scared to share this after 10 freaking years of waiting, but here we go: We found that temperature *perception* can change the biology of the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Krishna Singh Bisht
Macrophages excite muscle spindles with glutamate to bolster locomotion
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature
A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...
www.nature.com
December 4, 2024 at 5:08 PM
Macrophages excite muscle spindles with glutamate to bolster locomotion
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Krishna Singh Bisht
Reposted by Krishna Singh Bisht
