Albert Koulman
koulman.bsky.social
Albert Koulman
@koulman.bsky.social
Principal Research Associate at the IMS, University of Cambridge.
Head of the core Metabolomics and Lipidomics Lab
Head of the Nutritional Biomarker Lab
Interested in #lipidomics #metabolomics #massspec #biomarkers
All dietary assessment tools have limitation and it is therefore important to objectively determine the measurement error of the tool used. Within the National Diet and Nutrition Survey in the UK we do this regularly . See our recent paper with all the details.
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
September 26, 2025 at 7:12 AM
Just out: Folate status shows no relationship with vitamin B12 but reiterates the urgency for folate fortification in the UK.
The prevalence of folate deficiency was assessed based on the serum folate concentrations from 47,240 samples from Aug 2023 to Jan 2025.
link.springer.com/article/10.1...
September 8, 2025 at 12:24 PM
Reposted by Albert Koulman
Reposted by Albert Koulman
6/12 Transcriptional, proteomic and lipidomic analysis of our cell line models showed up-regulation of redox-protective pathways, alongside changes in lipids, including low levels of peroxisomal/ER ether-linked lipids, and high levels of ferroptosis-susceptible membrane PUFAs.
May 20, 2025 at 9:39 AM
Reposted by Albert Koulman
Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com‬. 🧵

www.nature.com/articles/s41...
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition - Nature Communications
CREBBP mutations in B-cell acute lymphoblastic leukemia (B-ALL) are linked to poor prognosis and chemoresistance. Here, the authors show that genetic or pharmacological inactivation of CREBBP sensitiz...
www.nature.com
May 20, 2025 at 9:34 AM
Reposted by Albert Koulman
Would be interesting to know how many injections other groups get out of columns in plasma peptidomics / proteomics experiments?

There are some huge studies out there looking at thousands of samples - how long do columns last? Share your experiences!! #proteomics #peptidomics #teammassspec
February 21, 2025 at 8:02 AM
For everyone in the Cambridge area interested in metabolomics or lipidomics: CaMeL talks, January 23rd. Please register on www.mrl.ims.cam.ac.uk/events/camel...
January 7, 2025 at 8:27 AM
Reposted by Albert Koulman
Not long now to apply to the @ims-mrl.bsky.social at the University of Cambridge for your postgrad studies next year in order to meet the funding deadline #MPhil #PhD #obesity #metabolism #diabetes
👇 👇 👇 👇
www.mrl.ims.cam.ac.uk/study-us/phd
www.mrl.ims.cam.ac.uk/study-us/tau...
November 27, 2024 at 10:44 AM
The saturated fatty acid palmitate (C16:0) is one of the most common fatty acids in our food. However, changing palmitate intake has little impact on the circulating levels. We still understand little of the real effect of saturated fat consumption.
November 22, 2024 at 12:22 PM
What are the normal concentrations of vitamin D in breast milk? We can only know when we have a suitable method. Here we present the validation of an LC-MS/MS method.

www.sciencedirect.com/science/arti...
The validation of an LC-MS/MS method for the quantification of vitamin D metabolites in human milk and their biological variability in Gambian women
Vitamin D is required for healthy growth and development, but data on human milk vitamin D content is limited. We describe a liquid chromatography tan…
www.sciencedirect.com
November 17, 2024 at 3:46 PM